不寻常的临床病例:捐肾患者的药物流产

S. P. Sinchikhin, Olga E. Nagaeva, Ekaterina S. Sinchikhina, Margarita D. Mustafaeva
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引用次数: 0

摘要

该研究介绍了药物流产和预防术后并发症的算法,临床有效率达 99.7%。此外,还介绍了一个独特的病例,该病例涉及使用药物终止一名患有慢性肾小球肾炎(影响其肾脏)和慢性肾盂肾炎(之前移植了第二个肾脏)的患者的短期妊娠。鉴于患者目前没有泌尿器官功能障碍,也没有任何躯体病变的临床恶化,医疗委员会决定在对患者进行动态监测的情况下允许药物流产。单次口服 600 毫克米非司酮,36 小时后每日两次服用 400 微克米索前列醇(每次口服),可有效终止意外妊娠,且对生殖器外疾病无不良影响。在流产后月经周期的第二阶段服用妊娠药物可防止卵巢功能紊乱和子宫内膜增生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unusual clinical case: Pharmabortion in a patient with a donor kidney
The study presents an algorithm for drug-induced abortion and prevention of complications after the procedure, with a clinical efficacy rate of 99.7%. In addition, a unique case is presented, involving the use of drugs to terminate a short-term pregnancy in a patient with chronic glomerulonephritis that affecting her kidney and chronic pyelonephritis in a previously transplanted second kidney. Given the lack of urinary organ dysfunction and the absence of clinical worsening of any somatic pathology at present, the medical consilium has determined that pharmabortion is permissible under dynamic monitoring of the patient. A single oral dose of 600 mg of mifepristone, followed by twice-daily administration of 400 mcg of misoprostol (per os) 36 h later, effectively terminated the unwanted pregnancy without adverse effects on extragenital diseases. Administering the gestagenic drug during the second phase of the menstrual cycle after abortion prevented ovarian dysfunction and endometrial hyperplasia.
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