通过可见光促进的镍催化 Ynones 分子内环化/氧化顺序合成吲哚基苯基二酮类化合物

IF 3.3 Q2 CHEMISTRY, MULTIDISCIPLINARY

ACS Organic & Inorganic Au Pub Date : 2023-12-21 DOI:10.1021/acsorginorgau.3c00060

Yufeng Zhou, Yaping Wang, Peidong Xu, Weiwei Han, Heng-Ying Xiong* and Guangwu Zhang*,

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引用次数: 0

摘要

将可见光催化与镍催化相结合，通过炔酮的环化/氧化过程合成了吲哚基苯基二酮。该反应在温和、无碱的条件下进行，为克级合成提供了广阔的空间和可行性。通过这种方法，一些天然产物和具有生物学意义的分子可以很容易地进行后官能化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis of Indolyl Phenyl Diketones through Visible-Light-Promoted Ni-Catalyzed Intramolecular Cyclization/Oxidation Sequence of Ynones

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Synthesis of Indolyl Phenyl Diketones through Visible-Light-Promoted Ni-Catalyzed Intramolecular Cyclization/Oxidation Sequence of Ynones

The combination of visible light catalysis and Ni catalysis has enabled the synthesis of indolyl phenyl diketones through the cyclization/oxidation process of ynones. This reaction proceeded under mild and base-free conditions and showed a broad scope and feasibility for gram-scale synthesis. Several natural products and biologically interesting molecules could be readily postfunctionalized by this method.

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来源期刊

ACS Organic & Inorganic Au 有机化学、无机化学-

CiteScore

4.10

自引率

0.00%

发文量

期刊介绍： ACS Organic & Inorganic Au is an open access journal that publishes original experimental and theoretical/computational studies on organic organometallic inorganic crystal growth and engineering and organic process chemistry. Short letters comprehensive articles reviews and perspectives are welcome on topics that include:Organic chemistry Organometallic chemistry Inorganic Chemistry and Organic Process Chemistry.