阻塞性睡眠呼吸暂停-低通气综合征。

IF 3.4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Nicola Read, Callum Jennings, Alanna Hare
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引用次数: 0

摘要

阻塞性睡眠呼吸暂停-低通气综合征(OSAHS)是一种常见疾病,其特点是睡眠期间咽部气道反复发生完全或部分塌陷。这会导致气流停止(呼吸暂停)或减少(低通气),从而导致血氧饱和度降低和睡眠破碎。一个人是否会患上 OSAHS 取决于其上气道的塌陷程度。塌陷程度可以通过周围组织的闭塞压力或腔外压力之间的平衡来量化。患者会出现打鼾、睡眠不清爽、目睹性呼吸暂停、醒来时有窒息感以及白天过度嗜睡等症状。OSAHS 会造成广泛的后果,包括心血管、新陈代谢和神经认知后遗症。治疗方案包括生活方式措施,尤其是减肥,以及在夜间保持上气道通畅的策略,包括持续气道正压、下颌前移器和体位调节器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Obstructive sleep apnoea-hypopnoea syndrome.

Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a common disorder characterised by repetitive episodes of the complete or partial collapse of the pharyngeal airway during sleep. This results in cessation (apnoea) or reduction (hypopnoea) of airflow, leading to oxygen desaturation and sleep fragmentation. An individual's disposition to develop OSAHS depends on the collapsibility of a segment of the upper airway. The degree of collapsibility can be quantified by the balance between occluding or extraluminal pressures of the surrounding tissues. Patients can experience snoring, unrefreshing sleep, witnessed apnoeas, waking with a choking sensation and excessive daytime sleepiness. OSAHS has a broad range of consequences, including cardiovascular, metabolic, and neurocognitive sequelae. Treatment options include lifestyle measures, in particular weight loss, and strategies to maintain upper airway patency overnight, including continuous positive airway pressure, mandibular advancement devices and positional modifiers.

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CiteScore
7.70
自引率
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