心包脂肪量和冠状动脉风险因素是冠状动脉钙化评分 = 0 的患者中存在非钙化冠状动脉斑块的预测因素。

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian heart journal Pub Date : 2024-01-01 DOI:10.1016/j.ihj.2023.12.006

Abdulameer A. Al-Mosawi , Hussein Nafakhi , Yusra Sahib Alabayechi

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引用次数: 0

摘要

导言：在 CAC = 0 的患者中，将心包脂肪量（PFV）和经典冠状动脉危险因素与非钙化斑块的存在联系起来的文献数据很少：共收集了 811 名胸痛提示心绞痛的患者，他们接受了 CT 冠状动脉造影术，以评估冠状动脉疾病。其中，417 名 CAC = 0 的患者被纳入分析：结果：非钙化斑块患者年龄较大（54±9 对 50±10，P = 0.01），糖尿病患病率较高（31% 对 17%，P = 0.02），体重指数较高（29.9 对 28.3，P = 0.04），PFV 增加（123 cm3 对 99 cm3，P 结论：CAC 评分为 0 的患者中，年龄最大的是男性（54±9 对 50±10，P = 0.01），年龄最小的是女性（54±9 对 50±10，P = 0.01）：在 CAC 得分为 0 的患者中，高龄、糖尿病、PFV 增加和高体重指数都与非钙化斑块的存在有关。经多变量调整后，体重指数增加仍是非钙化斑块存在的重要独立预测因素。

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Pericardial fat volume and coronary risk factors as predictors of non-calcified coronary plaque presence among patients with coronary calcium score = 0

Introduction

There is scarce data linking pericardial fat volume (PFV) and classical coronary risk factors with non-calcified plaque presence among patients with CAC = 0 in the literature.

Material and method

A total of 811 patients with chest pain suggestive of angina underwent CT coronary angiography for the assessment of coronary artery disease were collected. Of these, 417 with CAC = 0 were included in the analysis.

Result

Patients with non-calcified plaque were older (54 ± 9 versus 50 ± 10, P = 0.01) and had a higher prevalence of diabetes mellitus (31% versus 17%, P = 0.02), high BMI (29.9 versus 28.3, P = 0.04), and increased PFV (123 cm³ versus 99 cm³, P < 0.01) compared to patients without plaque. In multivariate regression analysis, high BMI[OR(CI) = 1.1(1–1.3), P = 0.02] was an independent predictor of non-calcified coronary plaque presence among patients with CAC = 0 after adjustment to variables with P < 0.05 in the univariate analysis.

Conclusion

In patients with a CAC score of 0, advanced age, diabetes mellitus, increased PFV, and high BMI were all associated with the presence of non-calcified plaque. After multivariate adjustment, increased BMI remained a significant independent predictor for non-calcified plaque presence.

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来源期刊

Indian heart journal CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.60

自引率

6.70%

发文量

审稿时长

52 days

期刊介绍： Indian Heart Journal (IHJ) is the official peer-reviewed open access journal of Cardiological Society of India and accepts articles for publication from across the globe. The journal aims to promote high quality research and serve as a platform for dissemination of scientific information in cardiology with particular focus on South Asia. The journal aims to publish cutting edge research in the field of clinical as well as non-clinical cardiology - including cardiovascular medicine and surgery. Some of the topics covered are Heart Failure, Coronary Artery Disease, Hypertension, Interventional Cardiology, Cardiac Surgery, Valvular Heart Disease, Pulmonary Hypertension and Infective Endocarditis. IHJ open access invites original research articles, research briefs, perspective, case reports, case vignette, cardiovascular images, cardiovascular graphics, research letters, correspondence, reader forum, and interesting photographs, for publication. IHJ open access also publishes theme-based special issues and abstracts of papers presented at the annual conference of the Cardiological Society of India.