遗传性大疱性表皮松解症患者的口腔修复康复:系统综述。

Salomé Mascarell, Hélène Citterio, Énora Le Roux, Ariane Berdal, Géraldine Lescaille, Lisa Friedlander
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引用次数: 0

摘要

遗传性大疱性表皮松解症(Epidermolysis bullosa hereditaria,EBH)是一组罕见的疾病,其特点是皮肤黏膜脆弱并形成大疱,包括口腔黏膜。治疗方法的选择,尤其是修复康复,必须在尊重患者的功能和美学期望的同时,预见到口腔开放限制的恶化。这篇关于遗传性表皮松解症(EBH)患者口腔修复康复的综述旨在研究现有文章的证据水平和质量,并为这些患者的修复治疗制定临床建议:2022 年 7 月,按照 PICOTS 要素在五个数据库中进行了电子检索。采用改良皮尔森、布拉德福德-希尔斯和渥太华-纽卡斯尔量表确定报告质量:从 19 份病例报告中提取的协议分析数据涉及 64 名患者和 80 个牙齿修复体,几乎每 10 名患者中就有 9 名完全无牙。EBH类型的分布为84%萎缩型、10.5%交界型和5.5%单纯型。本综述中作者们遇到的困难反映了牙科实践中最有可能遇到的困难。大多数修复是种植体支持的修复(85%),其次是活动假牙(10%),最后是牙科支持的修复(5%)。种植体支持的固定全拱修复体占种植体支持修复体的76.4%,这最后一种修复方案显示出最高的科学质量:在个体化治疗方法中,我们建议在全口无牙颌病例中,固定全弓种植体支持修复体是最合适的,因为在如此复杂的临床环境中,这种修复体可以实现最佳的计算机辅助规划、设计、制造和安装。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oral Prosthetic Rehabilitation in Patients with Epidermolysis Bullosa Hereditaria: A Systematic Review.

Purpose: To review the oral prosthetic rehabilitation of patients with epidermolysis bullosa hereditaria (EBH) and study the level of evidence and quality of the presented available articles and establish clinical recommendations for the prosthetic management of these patients.

Materials and methods: An electronic search was done in July 2022 in five databases following PICOTS elements. The quality of the reports was established using the modified Pierson, Bradford Hills, and Ottawa Newcastle scale.

Results: Data extracted from 19 case reports for protocolized analysis corresponded to 64 patients and 80 dental prostheses, with almost 9 out of 10 patients being completely edentulous. The distribution of EBH types was 84% dystrophic, 10.5% junctional, and 5.5% simplex. The difficulties encountered by the authors synthesized in this review characteristically reflected those most likely encountered in dental practice. Most rehabilitations were implant-supported prostheses (85%), followed by removable dentures (10%) and dental-supported rehabilitations (5%). Fixed full-arch implant-supported prostheses represented 76.4% of implant-supported prostheses, and this prosthetic solution reflected the highest scientific quality.

Conclusions: For an individualized approach to treatment, we recommend that in cases of total edentulism, fixed full-arch implant-supported prostheses are the most appropriate because they allow the best computer-aided planning, design, manufacture, and fitting of the prosthesis in such a complex clinical context.

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