{"title":"[摄入乙醇计算中的不确定性估计]。","authors":"G V Nedugov","doi":"10.17116/sudmed20236606140","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To develop a method of uncertainty estimate in calculation of ingested ethanol by E. Widmark formula and its realization as a computer program.</p><p><strong>Material and methods: </strong>The methodological design of the study was an analytical construction of the equation of uncertainty estimates of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic model. Mathematical analysis operations were performed independently, as well as using WolframAlfa web application. The computer program code was compiled in the C# programming language using the free version of Microsoft Visual Studio application.</p><p><strong>Results: </strong>The equation of uncertainty estimate of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic equation, with standard deviation of the sought value as its measure has been derived. The Alcohol Calculator V 5.0 application was created in the C# programming language. This program implements a complex of computational procedures related to the use of developed uncertainty equation, and allows to determine the confidence error intervals for estimates of ingested ethanol for any probability of error.</p><p><strong>Conclusion: </strong>The obtained equation of uncertainty estimates of the mass of ingested ethanol and the computer application implementing it are recommended for forensic medical evaluation of the kinetics of orally administered ethanol.</p>","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Uncertainty estimate in calculation of ingested ethanol].\",\"authors\":\"G V Nedugov\",\"doi\":\"10.17116/sudmed20236606140\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To develop a method of uncertainty estimate in calculation of ingested ethanol by E. Widmark formula and its realization as a computer program.</p><p><strong>Material and methods: </strong>The methodological design of the study was an analytical construction of the equation of uncertainty estimates of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic model. Mathematical analysis operations were performed independently, as well as using WolframAlfa web application. The computer program code was compiled in the C# programming language using the free version of Microsoft Visual Studio application.</p><p><strong>Results: </strong>The equation of uncertainty estimate of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic equation, with standard deviation of the sought value as its measure has been derived. The Alcohol Calculator V 5.0 application was created in the C# programming language. This program implements a complex of computational procedures related to the use of developed uncertainty equation, and allows to determine the confidence error intervals for estimates of ingested ethanol for any probability of error.</p><p><strong>Conclusion: </strong>The obtained equation of uncertainty estimates of the mass of ingested ethanol and the computer application implementing it are recommended for forensic medical evaluation of the kinetics of orally administered ethanol.</p>\",\"PeriodicalId\":35704,\"journal\":{\"name\":\"Sudebno-Meditsinskaya Ekspertisa\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sudebno-Meditsinskaya Ekspertisa\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17116/sudmed20236606140\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sudebno-Meditsinskaya Ekspertisa","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/sudmed20236606140","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的开发一种用 E. Widmark 公式计算摄入乙醇的不确定性估计方法，并将其实现为计算机程序：研究的方法设计是根据 E. Widmark 动力学模型，分析构建摄入乙醇质量不确定性估计方程。数学分析操作是独立进行的，同时还使用了 WolframAlfa 网络应用程序。计算机程序代码是使用微软 Visual Studio 免费版应用程序以 C# 编程语言编译的：结果：根据 E. Widmark 动力学方程得出了摄入乙醇质量的不确定性估计方程，并以所求值的标准偏差作为衡量标准。酒精计算器 V 5.0 应用程序是用 C# 编程语言创建的。该程序实现了与使用所开发的不确定性方程相关的复杂计算程序，并允许确定任何误差概率下摄入乙醇估算值的置信误差区间：结论：所获得的摄入乙醇质量不确定性估算方程和实现该方程的计算机应用程序推荐用于口服乙醇动力学的法医评估。
[Uncertainty estimate in calculation of ingested ethanol].
Objective: To develop a method of uncertainty estimate in calculation of ingested ethanol by E. Widmark formula and its realization as a computer program.
Material and methods: The methodological design of the study was an analytical construction of the equation of uncertainty estimates of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic model. Mathematical analysis operations were performed independently, as well as using WolframAlfa web application. The computer program code was compiled in the C# programming language using the free version of Microsoft Visual Studio application.
Results: The equation of uncertainty estimate of the mass of ingested ethanol, obtained on the basis of E. Widmark kinetic equation, with standard deviation of the sought value as its measure has been derived. The Alcohol Calculator V 5.0 application was created in the C# programming language. This program implements a complex of computational procedures related to the use of developed uncertainty equation, and allows to determine the confidence error intervals for estimates of ingested ethanol for any probability of error.
Conclusion: The obtained equation of uncertainty estimates of the mass of ingested ethanol and the computer application implementing it are recommended for forensic medical evaluation of the kinetics of orally administered ethanol.
期刊介绍：
The journal is concerned with the theory and practice of forensic medicine - the problems of thanatology, traumatology, toxicology, serology, forensic obstetrics, forensic dentistry, forensic psychiatry, forensic chemistry, physicotechnical methods of investigation, history of forensic medicine and some problems of criminology and legal laws related to forensic medicine. It publishes original studies by Russian authors, casuistry surveys, abstracts and reviews of Russian and foreign literature, scientific information, reports on scientific conferences.
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