炎症、抗炎药和秋水仙碱在颈动脉狭窄中的作用。

IF 2.1 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

Vasa-european Journal of Vascular Medicine Pub Date : 2024-01-01 Epub Date: 2023-12-11 DOI:10.1024/0301-1526/a001104

David-Dimitris Chlorogiannis, Sumant Pargaonkar, Panagiotis Papanagiotou, Nikolaos C Bakogiannis, Christos Bakoyiannis, Damianos G Kokkinidis

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引用次数: 0

摘要

心血管疾病是全球发病率和死亡率的主要原因。最近几年，人们研究了炎症和炎症调节药物在冠心病最佳治疗中的作用。我们可以假设，由于炎症也参与了颈动脉狭窄的发展和恶化，因此同一类药物也可能是有用的。我们撰写这篇综述的目的是介绍关于抗炎药物在颈动脉狭窄患者中的作用的现有证据、已发表的研究和正在进行的有希望的试验，重点是这类药物中最常用的药物：秋水仙碱。

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Inflammation, anti-inflammatory agents, and the role of colchicine in carotid artery stenosis.

Cardiovascular disease is a major cause of morbidity and mortality worldwide. In the last few years, the role of inflammation and inflammatory modulatory medications is investigated for the optimal treatment of coronary artery disease. It can be hypothesized that since inflammation is also involved in carotid artery stenosis development and progression, the same class of medication could be useful. Our objective with this review is to present the available evidence, published studies and promising ongoing trials on the role of anti-inflammatory medications - with a special emphasis on the most commonly used drug of this class: colchicine - in patients with carotid artery stenosis.

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来源期刊

Vasa-european Journal of Vascular Medicine 医学-外周血管病

CiteScore

3.90

自引率

11.10%

发文量

审稿时长

1 months

期刊介绍： Vasa is the European journal of vascular medicine. It is the official organ of the German, Swiss, and Slovenian Societies of Angiology. The journal publishes original research articles, case reports and reviews on vascular biology, epidemiology, prevention, diagnosis, medical treatment and interventions for diseases of the arterial circulation, in the field of phlebology and lymphology including the microcirculation, except the cardiac circulation. Vasa combines basic science with clinical medicine making it relevant to all physicians interested in the whole vascular field.