垂体功能减退症的生育问题。

IF 6.9 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Reviews in Endocrine & Metabolic Disorders Pub Date : 2024-06-01 Epub Date: 2023-12-14 DOI:10.1007/s11154-023-09863-9

Julie Chen, Julia J Chang, Esther H Chung, Ruth B Lathi, Lusine Aghajanova, Laurence Katznelson

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引用次数: 0

摘要

与垂体功能正常的妇女相比，患有垂体功能减退症的妇女生育率较低，妊娠结局也较差。尽管使用了辅助生殖技术和激素替代品，但这些差异依然存在。对于性腺功能减退的妇女，可以使用外源性促性腺激素来成功诱导排卵。有人认为，在生长激素缺乏的情况下补充生长激素可增强生殖功能，但其在垂体功能低下妇女中的常规应用仍不明确，需要进一步研究。在本综述中，我们将讨论垂体功能减退症妇女生育的临床方法。

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Fertility issues in hypopituitarism.

Women with hypopituitarism have lower fertility rates and worse pregnancy outcomes than women with normal pituitary function. These disparities exist despite the use of assisted reproductive technologies and hormone replacement. In women with hypogonadotropic hypogonadism, administration of exogenous gonadotropins can be used to successfully induce ovulation. Growth hormone replacement in the setting of growth hormone deficiency has been suggested to potentiate reproductive function, but its routine use in hypopituitary women remains unclear and warrants further study. In this review, we will discuss the clinical approach to fertility in a woman with hypopituitarism.

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来源期刊

Reviews in Endocrine & Metabolic Disorders 医学-内分泌学与代谢

CiteScore

14.70

自引率

1.20%

发文量

审稿时长

>12 weeks

期刊介绍： Reviews in Endocrine and Metabolic Disorders is an international journal dedicated to the field of endocrinology and metabolism. It aims to provide the latest advancements in this rapidly advancing field to students, clinicians, and researchers. Unlike other journals, each quarterly issue of this review journal focuses on a specific topic and features ten to twelve articles written by world leaders in the field. These articles provide brief overviews of the latest developments, offering insights into both the basic aspects of the disease and its clinical implications. This format allows individuals in all areas of the field, including students, academic clinicians, and practicing clinicians, to understand the disease process and apply their knowledge to their specific areas of interest. The journal also includes selected readings and other essential references to encourage further in-depth exploration of specific topics.