全基因组测序揭示关中奶山羊产奶性状相关候选基因

IF 1.8 3区生物学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Animal genetics Pub Date : 2023-12-13 DOI:10.1111/age.13380

Jie Ni, Ming Xian, Yijie Ren, Lina Yang, Yu Li, Songmao Guo, Benkang Ran, Jianhong Hu

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引用次数: 0

摘要

产奶是山羊最重要的经济价值之一。关中奶山羊是中国陕西省的地方奶山羊，产奶量高，奶质好。然而，有关关中奶山羊产奶性状分子标记的研究相对较少。在本研究中，我们对 20 只关中奶山羊进行了全基因组测序，其中 10 只为高产奶山羊（HM），10 只为低产奶山羊（LM）。我们利用Fst和π-ratio统计量检测了高产奶量奶山羊的候选选择特征，并确定了几个与产奶量相关的候选基因，包括ANPEP、ADRA1A和PRKG1。我们的研究结果为关中奶山羊产奶性状的分子育种提供了依据。

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Whole-genome resequencing reveals candidate genes associated with milk production trait in Guanzhong dairy goats

Milk production is one of the most important economic utility of goats. Guanzhong dairy goat is a local dairy goat in Shaanxi Province of China and has high milk yield and quality. However, there are relatively few studies on molecular markers of milk production traits in Guanzhong dairy goats. In this study, we sequenced the whole genomes of 20 Guanzhong dairy goats, 10 of which had high milk yield (HM) and 10 of which had low milk yield (LM). We detected candidate signatures of selection in HM goats using F_st and π-ratio statistics and identified several candidate genes including ANPEP, ADRA1A and PRKG1 associated with milk production. Our results provide the basis for molecular breeding of milk production traits in Guanzhong dairy goats.

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来源期刊

Animal genetics 生物-奶制品与动物科学

CiteScore

4.60

自引率

4.20%

发文量

115

审稿时长

5 months

期刊介绍： Animal Genetics reports frontline research on immunogenetics, molecular genetics and functional genomics of economically important and domesticated animals. Publications include the study of variability at gene and protein levels, mapping of genes, traits and QTLs, associations between genes and traits, genetic diversity, and characterization of gene or protein expression and control related to phenotypic or genetic variation. The journal publishes full-length articles, short communications and brief notes, as well as commissioned and submitted mini-reviews on issues of interest to Animal Genetics readers.