抑制 MAT2A 可抑制受牙龈卟啉单胞菌感染的人牙龈成纤维细胞的炎症反应

IF 3.7 2区医学 Q2 MICROBIOLOGY

Journal of Oral Microbiology Pub Date : 2023-12-15 DOI:10.1080/20002297.2023.2292375

Lishan Jiang, Jingwen Li, Kun Ji, Lang Lei, Houxuan Li

引用次数: 0

摘要

蛋氨酸腺苷转移酶 II alpha（MAT2A）是将蛋氨酸转化为 S-腺苷蛋氨酸（SAM）的关键酶，SAM 是参与甲基化的主要甲基基团供体。MAT2A的作用是...

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MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts

Methionine adenosyl transferase II alpha (MAT2A) is the key enzyme to transform methionine into S-adenosylmethionine (SAM), the main methylgroup donor involved in the methylation. The purpose of ou...

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来源期刊

Journal of Oral Microbiology MICROBIOLOGY-

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

12 weeks

期刊介绍： As the first Open Access journal in its field, the Journal of Oral Microbiology aims to be an influential source of knowledge on the aetiological agents behind oral infectious diseases. The journal is an international forum for original research on all aspects of ''oral health''. Articles which seek to understand ''oral health'' through exploration of the pathogenesis, virulence, host-parasite interactions, and immunology of oral infections are of particular interest. However, the journal also welcomes work that addresses the global agenda of oral infectious diseases and articles that present new strategies for treatment and prevention or improvements to existing strategies. Topics: ''oral health'', microbiome, genomics, host-pathogen interactions, oral infections, aetiologic agents, pathogenesis, molecular microbiology systemic diseases, ecology/environmental microbiology, treatment, diagnostics, epidemiology, basic oral microbiology, and taxonomy/systematics. Article types: original articles, notes, review articles, mini-reviews and commentaries