2003 年至 2019 年美国全国自杀和男性双胞胎活产趋势:对集体乐观主义和胎儿选择的最新检验

IF 1 4区 医学 Q4 GENETICS & HEREDITY
Parvati Singh, Samantha Gailey, Abhery Das, Tim A. Bruckner
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引用次数: 0

摘要

之前基于瑞典数据的研究表明,以月度自杀发生率衡量的集体乐观情绪与子宫内对男性双胞胎的选择成反比。美国是所有高收入国家中自杀率最高的国家,我们在美国检验了这一发现,并研究了总体自杀率的月度变化是否先于男性双胞胎与男性单胎活产比例的变化。与之前的研究一致,我们也将 15-49 岁女性的自杀率作为一个关键的自变量进行研究。我们从疾病预防控制中心 WONDER 中检索了 2003 年至 2019 年自杀率和男性双胞胎与男性单胎活产率的月度数据,并应用 Box-Jenkins 迭代时间序列例程检测和消除了这两个序列的自相关性。结果表明,总体自杀率的月度变化每增加 1%,6 个月后男性双胞胎活产率就会下降 0.005 个单位(系数 = -.005,P 值 = .004)。使用育龄妇女自杀作为自变量(系数 = -.0012,P 值 = .014),结果仍然稳健。我们的研究为之前的研究提供了外部有效性,并支持了集体乐观情绪的下降与子宫内更大的选择性相对应这一观点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
National Trends in Suicides and Male Twin Live Births in the US, 2003 to 2019: An Updated Test of Collective Optimism and Selection in Utero
Prior research based on Swedish data suggests that collective optimism, as measured by monthly incidence of suicides, correlates inversely with selection in utero against male twins in a population. We test this finding in the US, which reports the highest suicide rate of all high-income countries, and examine whether monthly changes in overall suicides precede changes in the ratio of male twin to male singleton live births. Consistent with prior work, we also examine as a key independent variable, suicides among women aged 15−49 years. We retrieved monthly data on suicides and the ratio of male twin to singleton live births from CDC WONDER, 2003 to 2019, and applied Box-Jenkins iterative time-series routines to detect and remove autocorrelation from both series. Results indicate that a 1% increase in monthly change in overall suicides precedes a 0.005 unit decline in male twin live births ratio 6 months later (coefficient = −.005, p value = .004). Results remain robust to use of suicides among reproductive-aged women as the independent variable (coefficient = −.0012, p value = .014). Our study lends external validity to prior research and supports the notion that a decline in collective optimism corresponds with greater selection in utero.
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来源期刊
Twin Research and Human Genetics
Twin Research and Human Genetics 医学-妇产科学
CiteScore
1.50
自引率
11.10%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.
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