[撤稿] 罗替诺酮通过 PI3K/AKT 通路抑制裸鼠结肠癌细胞的活力、运动性、上皮-间质转化和肿瘤发生。

IF 5.7 3区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
Wenbo Xiao, Yongwei Liu, Maolin Dai, Yu Li, Renqun Peng, Shuangjiang Yu, Hao Liu
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引用次数: 0

摘要

这篇论文发表后,一位读者提请编辑注意,图 3C 所示的免疫荧光染色数据以及图 4C 和 4D 所示的迁移和侵袭试验数据与不同研究机构不同作者撰写的其他研究文章中以不同形式出现的数据惊人地相似,这些文章有的已经发表,有的大约在同一时间提交发表,其中一篇已被撤回。此外,图 5 中显示的 E-cadherin 和 AKT 蛋白条带的 Western 印迹数据惊人地相似,尽管条带被垂直翻转了。由于上述文章中有争议的数据在提交给《国际分子医学杂志》之前已经在其他地方发表,因此编辑决定从该杂志上撤下这篇论文。已要求作者就这些问题做出解释,但编辑部没有收到回复。对于给读者带来的不便,编辑深表歉意。[国际分子医学杂志 44:700-708, 2020; DOI: 10.3892/ijmm.2020.4637]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Retracted] Rotenone restrains colon cancer cell viability, motility and epithelial‑mesenchymal transition and tumorigenesis in nude mice via the PI3K/AKT pathway.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the immunofluorescence staining data shown in Fig. 3C, and the migration and invasion assay data shown in Figs. 4C and 4D were strikingly similar to data appearing in different form in other research articles written by different authors at different research institutes that had either already been published, or were submitted for publication at around the same time, one of which has been retracted. In addition, the western blotting data shown for the E‑cadherin and AKT protein bands in Fig. 5 were strikingly similar, albeit the bands had been flipped vertically. Owing to the fact that contentious data in the above article had already been submitted for publication elsewhere prior to its submission to International Journal of Molecular Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Molecular Medicine 44: 700‑708, 2020; DOI: 10.3892/ijmm.2020.4637].
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来源期刊
International journal of molecular medicine
International journal of molecular medicine 医学-医学:研究与实验
CiteScore
12.30
自引率
0.00%
发文量
124
审稿时长
3 months
期刊介绍: The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality. The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research. All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
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