{"title":"胃肠道内热肥胖症患者的猫肠嵌入术效果:随机对照试验","authors":"Qingqing Zhu , Jian Cheng , Xiaolan Xu , Tangying Xu , Xingjiang Gu , Yun Xia , Lingzhen Mao , Nannan Hu , Yuexia Fang","doi":"10.1016/j.eujim.2023.102327","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Globally, the incidence of obesity is increasing, causing increased rates of hypertension, diabetes, and cardiovascular diseases. Acupoint catgut embedding, a popular acupuncture method in China, has greater efficacy than acupuncture for weight control. The effectiveness of catgut embedding in patients with fatty liver associated with metabolic dysfunction was investigated.</p></div><div><h3>Methods</h3><p>In this randomised controlled trial, 60 patients with gastrointestinal internal heat-type obesity were randomised to the intervention (<em>n</em> = 30) and control (<em>n</em> = 30) groups. The intervention group participated in the catgut embeddings with diet and exercise for 2 months, with a catgut treatment frequency of once every 10 days for 30 min. The control group participated only in diet and exercise for the same period. Body weight; body mass index (BMI); waist-to-hip ratio (WHR); fasting plasma glucose, 2-hour blood glucose, glycated haemoglobin, and lipid levels were assessed before and after treatments.</p></div><div><h3>Results</h3><p>Fifty-seven patients completed the courses. After 2 months, the intervention group showed a statistically significant trend of decrease in WHR and total score of gastrointestinal internal heat-type clinical symptoms when compared with the control group (mean difference: −0.03, 95 % confidence level [CI]: −0.07 to 0.00 and mean difference: −6.04, 95 % CI: −8.59 to −3.50, respectively). In the intervention group, the mean reductions in body weight and BMI were 6.18 kg (95 % CI: 4.60 to 7.76) and 2.23 kg/m<sup>2</sup> (95 % CI: 1.72 to 2.74), respectively. The total treatment efficiency for fatty liver in the intervention and control groups was 61.5 % and 30.8 %, respectively (risk ratio: 3.60; 95 % CI: 1.14 to 11.35).</p></div><div><h3>Conclusion</h3><p>Catgut embedding administered with diet and exercise is effective for patients with gastrointestinal internal heat-type obesity and some patients with obesity complicated by metabolic dysfunction-associated fatty liver disease. The effects observed in the intervention group were superior to those in the control group in terms of body weight, BMI, WHR, total score of gastrointestinal internal heat-type clinical symptoms, and treatment effectiveness for metabolic dysfunction-associated fatty liver disease. There were no serious adverse reactions during the treatment.</p></div><div><h3>Registration number</h3><p>ChiCTR2200057237.</p></div><div><h3>Funding</h3><p>This study was supported by the Hangzhou Medicine and Health Science and Technology Program and Hangzhou Lin'an District Hospital of Traditional Chinese Medicine.</p></div>","PeriodicalId":11932,"journal":{"name":"European Journal of Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1876382023001038/pdfft?md5=1e0505cc3272ba77d025c5185e34708c&pid=1-s2.0-S1876382023001038-main.pdf","citationCount":"0","resultStr":"{\"title\":\"The effects of catgut embedding in patients with obesity of gastrointestinal internal heat: A randomised controlled trial\",\"authors\":\"Qingqing Zhu , Jian Cheng , Xiaolan Xu , Tangying Xu , Xingjiang Gu , Yun Xia , Lingzhen Mao , Nannan Hu , Yuexia Fang\",\"doi\":\"10.1016/j.eujim.2023.102327\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Globally, the incidence of obesity is increasing, causing increased rates of hypertension, diabetes, and cardiovascular diseases. Acupoint catgut embedding, a popular acupuncture method in China, has greater efficacy than acupuncture for weight control. The effectiveness of catgut embedding in patients with fatty liver associated with metabolic dysfunction was investigated.</p></div><div><h3>Methods</h3><p>In this randomised controlled trial, 60 patients with gastrointestinal internal heat-type obesity were randomised to the intervention (<em>n</em> = 30) and control (<em>n</em> = 30) groups. The intervention group participated in the catgut embeddings with diet and exercise for 2 months, with a catgut treatment frequency of once every 10 days for 30 min. The control group participated only in diet and exercise for the same period. Body weight; body mass index (BMI); waist-to-hip ratio (WHR); fasting plasma glucose, 2-hour blood glucose, glycated haemoglobin, and lipid levels were assessed before and after treatments.</p></div><div><h3>Results</h3><p>Fifty-seven patients completed the courses. After 2 months, the intervention group showed a statistically significant trend of decrease in WHR and total score of gastrointestinal internal heat-type clinical symptoms when compared with the control group (mean difference: −0.03, 95 % confidence level [CI]: −0.07 to 0.00 and mean difference: −6.04, 95 % CI: −8.59 to −3.50, respectively). In the intervention group, the mean reductions in body weight and BMI were 6.18 kg (95 % CI: 4.60 to 7.76) and 2.23 kg/m<sup>2</sup> (95 % CI: 1.72 to 2.74), respectively. The total treatment efficiency for fatty liver in the intervention and control groups was 61.5 % and 30.8 %, respectively (risk ratio: 3.60; 95 % CI: 1.14 to 11.35).</p></div><div><h3>Conclusion</h3><p>Catgut embedding administered with diet and exercise is effective for patients with gastrointestinal internal heat-type obesity and some patients with obesity complicated by metabolic dysfunction-associated fatty liver disease. The effects observed in the intervention group were superior to those in the control group in terms of body weight, BMI, WHR, total score of gastrointestinal internal heat-type clinical symptoms, and treatment effectiveness for metabolic dysfunction-associated fatty liver disease. There were no serious adverse reactions during the treatment.</p></div><div><h3>Registration number</h3><p>ChiCTR2200057237.</p></div><div><h3>Funding</h3><p>This study was supported by the Hangzhou Medicine and Health Science and Technology Program and Hangzhou Lin'an District Hospital of Traditional Chinese Medicine.</p></div>\",\"PeriodicalId\":11932,\"journal\":{\"name\":\"European Journal of Integrative Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1876382023001038/pdfft?md5=1e0505cc3272ba77d025c5185e34708c&pid=1-s2.0-S1876382023001038-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Integrative Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1876382023001038\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Integrative Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1876382023001038","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
The effects of catgut embedding in patients with obesity of gastrointestinal internal heat: A randomised controlled trial
Introduction
Globally, the incidence of obesity is increasing, causing increased rates of hypertension, diabetes, and cardiovascular diseases. Acupoint catgut embedding, a popular acupuncture method in China, has greater efficacy than acupuncture for weight control. The effectiveness of catgut embedding in patients with fatty liver associated with metabolic dysfunction was investigated.
Methods
In this randomised controlled trial, 60 patients with gastrointestinal internal heat-type obesity were randomised to the intervention (n = 30) and control (n = 30) groups. The intervention group participated in the catgut embeddings with diet and exercise for 2 months, with a catgut treatment frequency of once every 10 days for 30 min. The control group participated only in diet and exercise for the same period. Body weight; body mass index (BMI); waist-to-hip ratio (WHR); fasting plasma glucose, 2-hour blood glucose, glycated haemoglobin, and lipid levels were assessed before and after treatments.
Results
Fifty-seven patients completed the courses. After 2 months, the intervention group showed a statistically significant trend of decrease in WHR and total score of gastrointestinal internal heat-type clinical symptoms when compared with the control group (mean difference: −0.03, 95 % confidence level [CI]: −0.07 to 0.00 and mean difference: −6.04, 95 % CI: −8.59 to −3.50, respectively). In the intervention group, the mean reductions in body weight and BMI were 6.18 kg (95 % CI: 4.60 to 7.76) and 2.23 kg/m2 (95 % CI: 1.72 to 2.74), respectively. The total treatment efficiency for fatty liver in the intervention and control groups was 61.5 % and 30.8 %, respectively (risk ratio: 3.60; 95 % CI: 1.14 to 11.35).
Conclusion
Catgut embedding administered with diet and exercise is effective for patients with gastrointestinal internal heat-type obesity and some patients with obesity complicated by metabolic dysfunction-associated fatty liver disease. The effects observed in the intervention group were superior to those in the control group in terms of body weight, BMI, WHR, total score of gastrointestinal internal heat-type clinical symptoms, and treatment effectiveness for metabolic dysfunction-associated fatty liver disease. There were no serious adverse reactions during the treatment.
Registration number
ChiCTR2200057237.
Funding
This study was supported by the Hangzhou Medicine and Health Science and Technology Program and Hangzhou Lin'an District Hospital of Traditional Chinese Medicine.
期刊介绍:
The European Journal of Integrative Medicine (EuJIM) considers manuscripts from a wide range of complementary and integrative health care disciplines, with a particular focus on whole systems approaches, public health, self management and traditional medical systems. The journal strives to connect conventional medicine and evidence based complementary medicine. We encourage submissions reporting research with relevance for integrative clinical practice and interprofessional education.
EuJIM aims to be of interest to both conventional and integrative audiences, including healthcare practitioners, researchers, health care organisations, educationalists, and all those who seek objective and critical information on integrative medicine. To achieve this aim EuJIM provides an innovative international and interdisciplinary platform linking researchers and clinicians.
The journal focuses primarily on original research articles including systematic reviews, randomized controlled trials, other clinical studies, qualitative, observational and epidemiological studies. In addition we welcome short reviews, opinion articles and contributions relating to health services and policy, health economics and psychology.