美国系统性红斑狼疮治疗方法行业赞助临床试验的地域和人口代表性。

Joshua J Skydel, Reshma Ramachandran, Sakinah Suttiratana, Joseph S Ross, Christopher M Burns, Joshua D Wallach
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引用次数: 0

摘要

在过去的20年里,由于发现了新的靶向途径,对系统性红斑狼疮(SLE)潜在治疗方法的临床研究有所增加,但对于哪些患者从新疗法中受益仍然存在不确定性黑人患者和其他少数群体,他们不成比例地经历了严重的疾病,在SLE试验中的代表性不足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Geographic and Demographic Representation in Industry-Sponsored, US-Based Clinical Trials of Systemic Lupus Erythematosus Therapies.
Clinical research into potential therapies for systemic lupus erythematosus (SLE) has increased over the last 2 decades, driven by the discovery of new targetable pathways, yet uncertainty persists over which patients benefit from new therapies.1 Black patients and other minoritized populations, which disproportionately experience severe disease, are underrepresented in SLE trials.2.
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