心脏干预对先天性心脏病营养不良儿童营养状况的短期影响--来自非洲发展中国家埃塞俄比亚的报告

IF 1.7 Q2 PEDIATRICS
Kidist Tesfaye, Temesgen Tsega
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引用次数: 0

摘要

背景与目的营养不良是婴幼儿先天性心脏缺损的常见问题,对其预后有重要影响。本研究旨在评估矫正性心脏干预对先天性心脏缺陷营养不良儿童生长恢复的短期影响。方法回顾性队列研究,为期一年(2021年4月至2022年4月),检索了5年(2017-2021年)儿童心脏矫正干预的数据。我们招募了年龄小于18岁并接受过心脏矫正干预的先天性心脏病患儿。术前确认营养不良的儿童术后随访6个月。在干预前和纠正后共6个月,每3个月使用人体测量测量结果。结果共纳入148例2月龄至18岁儿童,平均年龄5岁。无精子型冠心病占93.2%。干预前体重不足、消瘦和发育迟缓的比例分别为54%、54.1%和59.5%,干预后第3、6个月分别降至40.7%、39.2%、49.2%和29.3%、25.9%、34.8%。干预后营养不良的预测因子为冠心病类型、矫正年龄、PAH、干预类型,并进行总结。干预后第3个月和第6个月WFH和HFA的z分数比较显示较基线有显著改善。那些患有多环芳烃和矫正年龄较大的受试者体重过轻和消瘦的可能性更大。结论营养不良在冠心病患儿中很常见,与肺动脉高压的存在和校正年龄的增大有关。在6个多月的随访中,矫正性心脏干预显著改善了营养状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-Term Impact of Cardiac Intervention on the Nutritional Status of Malnourished Children with Congenital Heart Disease – A Report from a Developing African Country, Ethiopia
Background and Objective Malnutrition is a common problem in infants and children with congenital heart defect and has an impact on the disease outcome. This study aimed to assess the short-term impact of corrective cardiac intervention on growth recovery of malnourished children with congenital heart defects. Methods A retrospective cohort study was conducted over a year period (April 2021 to April 2022) by retrieving data from pediatric corrective cardiac interventions performed over a period of 5 years (2017–2021). We enrolled pediatric patients with congenital heart disease whose age is less than 18 years and have undergone corrective cardiac intervention. Those children identified to have malnutrition pre-operatively have been followed for 6 months postoperatively. Anthropometry measurements were used to measure the outcome, before intervention and every 3 months for a total of 6 months after correction. Results A total of 148 children from age 2 months to 18 years with a mean age of 5 years were included in the study. Most of the subjects had acyanotic CHD accounting for 93.2%. Magnitudes of underweight, wasting and stunting at pre intervention were 54%, 54.1% and 59.5% respectively, decreased to 40.7%, 39.2%, 49.2% and 29.3%, 25.9%, 34.8% at the 3rd and 6th month of the post intervention period respectively. Predictors of undernutrition at post intervention were type of CHD, age at correction, PAH, type of intervention and were summarized. Comparison of Z-scores for WFH and HFA on the 3rd and 6th month post intervention has shown significant improvement from baseline. Those subjects with PAH and older age at correction have a greater chance of being underweight and wasted. Conclusion Malnutrition is very common in children with CHD and is predicted by the presence of pulmonary hypertension and older age at correction. Corrective cardiac intervention significantly improved nutritional status during the follow-up over 6 months.
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