碳纳米管和石墨烯材料作为生物系统中的异生物体：是否就其安全性达成共识？

IF 6.8 Q1 TOXICOLOGY

Journal of Xenobiotics Pub Date : 2023-12-01 DOI:10.3390/jox13040047

David Gendron, G. Bubak

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引用次数: 0

摘要

碳纳米管和石墨烯是两种具有独特性能的纳米材料，在生物医学、储能和气体传感等领域具有潜在的应用前景。然而，关于这些材料的安全性仍存在争议，并且尚未就其对人类健康和环境的潜在风险达成完全共识。虽然一些研究对职业接触限值提出了建议，但需要进行更多的研究，以充分了解这些材料对人类健康和环境的潜在风险。在这篇综述中，我们将从碳纳米管和石墨烯及其复合材料的生物相容性和对生物系统的毒性等方面总结它们的优缺点。此外，我们概述了目前有关碳基纳米材料安全性的政策指导方针和技术法规。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Carbon Nanotubes and Graphene Materials as Xenobiotics in Living Systems: Is There a Consensus on Their Safety?

Carbon nanotubes and graphene are two types of nanomaterials that have unique properties and potential applications in various fields, including biomedicine, energy storage, and gas sensing. However, there is still a debate about the safety of these materials, and there is yet to be a complete consensus on their potential risks to human health and the environment. While some studies have provided recommendations for occupational exposure limits, more research is needed to fully understand the potential risks of these materials to human health and the environment. In this review, we will try to summarize the advantages and disadvantages of using carbon nanotubes and graphene as well as composites containing them in the context of their biocompatibility and toxicity to living systems. In addition, we overview current policy guidelines and technical regulations regarding the safety of carbon-based nanomaterials.

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来源期刊

Journal of Xenobiotics TOXICOLOGY-

CiteScore

5.30

自引率

1.70%

发文量

审稿时长

10 weeks

期刊介绍： The Journal of Xenobiotics publishes original studies concerning the beneficial (pharmacology) and detrimental effects (toxicology) of xenobiotics in all organisms. A xenobiotic (“stranger to life”) is defined as a chemical that is not usually found at significant concentrations or expected to reside for long periods in organisms. In addition to man-made chemicals, natural products could also be of interest if they have potent biological properties, special medicinal properties or that a given organism is at risk of exposure in the environment. Topics dealing with abiotic- and biotic-based transformations in various media (xenobiochemistry) and environmental toxicology are also of interest. Areas of interests include the identification of key physical and chemical properties of molecules that predict biological effects and persistence in the environment; the molecular mode of action of xenobiotics; biochemical and physiological interactions leading to change in organism health; pathophysiological interactions of natural and synthetic chemicals; development of biochemical indicators including new “-omics” approaches to identify biomarkers of exposure or effects for xenobiotics.