Development of Research on the Etiology and Pathogenesis of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 6-20% of women of childbearing age (Zafar U, Memon Z, Moin K, et al, 2019). It usually manifests as anovulation or rare ovulation, hirsutism, polycystic ovary changes, and quite common insulin resistance. Due to the heterogeneity of clinical manifestations, there is currently no unified international standard for the diagnosis of PCOS. The etiology and pathogenesis of this syndrome are not fully understood and are generally considered a multifactorial disease with various genetic, endocrine, and metabolic abnormalities.