锥体外系症状评定量表及其缩略版:临床测量特性评述

IF 16.3 1区 医学 Q1 PSYCHIATRY
Guy Chouinard, F. Cosci, V. Chouinard, Larry Alphs
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引用次数: 0

摘要

背景:锥体外系症状评定量表-简略版(ESRS- a)是锥体外系症状评定量表(ESRS)的简略版,具有说明、定义和半结构化访谈,遵循测量临床症状的临床计量概念。与ESRS类似,ESRS- a被开发用于评估四种类型的药物性运动障碍(DIMD):帕金森病、静坐症、肌张力障碍和迟发性运动障碍(TD)。摘要:目前的文献综述提供了ESRS和ESRS- a在临床研究中显示的最相关的临床计量学特性。提供了全面的ESRS-A定义,官方规模和基本说明。在两项关键性研究和多中心国际研究中评估了ESRS量表间的可靠性。评估抗精神病药物引起的运动障碍和特发性帕金森病的评分间信度很高。还为评级机构之间的可靠性和评级机构核证程序制定了准则。ESRS显示了良好的并发效度,td定义病例的异常不自主运动量表(AIMS)与ESRS定义病例的一致性为96%。同样,ESRS-A的帕金森病、无运动障碍、肌张力障碍和运动障碍的总分和分值的并发效度范围从好到非常好。在接受安慰剂、抗精神病药物、抗帕金森和抗运动障碍药物治疗后,ESRS对检测与dimd相关的运动差异特别敏感。ESRS测量药物引起的锥体外系症状被证明可以区分锥体外系症状和精神症状。关键信息:ESRS和ESRS- a是测量DIMD的有效临床指标。它们可以在临床研究中有价值地实施,特别是在抗精神病药物的试验中,以及在诊所中检测运动障碍的存在、严重程度和治疗反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Extrapyramidal Symptom Rating Scale and Its Abbreviated Version: A Critical Review of Clinimetric Properties
Background: The Extrapyramidal Symptom Rating Scale – Abbreviated (ESRS-A) is an abbreviated version of the Extrapyramidal Symptom Rating Scale (ESRS) with instructions, definitions, and a semi-structured interview that follows clinimetric concepts of measuring clinical symptoms. Similar to the ESRS, the ESRS-A was developed to assess four types of drug-induced movement disorders (DIMD): parkinsonism, akathisia, dystonia, and tardive dyskinesia (TD). Summary: The present review of the literature provides the most relevant clinimetric properties displayed by the ESRS and ESRS-A in clinical studies. Comprehensive ESRS-A definitions, official scale, and basic instructions are provided. ESRS inter-rater reliability was evaluated in two pivotal studies and in multicenter international studies. Inter-rater reliability was high for assessing both antipsychotic-induced movement disorders and idiopathic Parkinson’s disease. Guidelines were also established for inter-rater reliability and the rater certification processes. The ESRS showed good concurrent validity with 96% agreement between Abnormal Involuntary Movement Scale (AIMS) for TD-defined cases and ESRS-defined cases. Similarly, concurrent validity for ESRS-A total and subscores for parkinsonism, akathisia, dystonia, and dyskinesia ranged from good to very good. The ESRS was particularly sensitive for detecting DIMD-related movement differences following treatment with placebo, antipsychotics, and antiparkinsonian and antidyskinetic medications. ESRS measurement of drug-induced extrapyramidal symptoms was shown to discriminate extrapyramidal symptoms from psychiatric symptoms. Key Messages: The ESRS and ESRS-A are valid clinimetric indices for measuring DIMD. They can be valuably implemented in clinical research, particularly in trials testing antipsychotic medications, and in clinics to detect the presence, severity, and response to treatment of movement disorders.
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来源期刊
Psychotherapy and Psychosomatics
Psychotherapy and Psychosomatics 医学-精神病学
CiteScore
29.40
自引率
6.10%
发文量
46
期刊介绍: Psychotherapy and Psychosomatics is a reputable journal that has been published since 1953. Over the years, it has gained recognition for its independence, originality, and methodological rigor. The journal has been at the forefront of research in psychosomatic medicine, psychotherapy research, and psychopharmacology, and has contributed to the development of new lines of research in these areas. It is now ranked among the world's most cited journals in the field. As the official journal of the International College of Psychosomatic Medicine and the World Federation for Psychotherapy, Psychotherapy and Psychosomatics serves as a platform for discussing current and controversial issues and showcasing innovations in assessment and treatment. It offers a unique forum for cutting-edge thinking at the intersection of medical and behavioral sciences, catering to both practicing clinicians and researchers. The journal is indexed in various databases and platforms such as PubMed, MEDLINE, Web of Science, Science Citation Index, Social Sciences Citation Index, Science Citation Index Expanded, BIOSIS Previews, Google Scholar, Academic Search, and Health Research Premium Collection, among others.
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