医疗保健领域新出现的细菌和真菌病原体以及耐药性的威胁

Khaled Swailem Alzahrani, Khulood Majed Almutairi, A. Alsulami, Abdulrhman Mohmmed Aseeri, Mohammed Ahmed Alqarni, Arwa Ahmad Haffah, Muhannad Fahad Alqahtani, Mohammed Fahad Almistadi, Saad Ali Bin Muaddi, H. A. Ayoub
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引用次数: 0

摘要

由于耐药性持续上升,在卫生保健设施中管理真菌感染的治疗极为重要。制定监督抗生素使用的计划至关重要,这有助于减少耐药性的出现。快速诊断工具,如聚合酶链反应和下一代测序(PCR和NGS)有助于制定靶向治疗计划。实施严格的感染控制协议可以有效地减少卫生保健设施内的感染传播。专家之间的合作努力确保针对耐药性概况的定制治疗计划。对抗不断演变的耐药性涉及联合治疗和免疫治疗等方法。对卫生保健工作者和患者进行感染预防和控制教育至关重要。监测和流行病学在追踪耐药性模式方面发挥作用,从而指导干预措施。由于旅行模式,国际合作至关重要。持续的研究和创新对于提供治疗有效性和耐药性机制的管理至关重要。耐药性的临床意义,如严重程度增加、治疗失败和选择有限,强调了采取一种方法的必要性。总之,必须制定临床管理策略,以应对新出现的药物病原体带来的挑战,同时保障患者的预后和公共卫生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emerging bacterial and fungal pathogens in healthcare and the threat of drug resistance
Managing the treatment of fungal infections, in healthcare facilities is extremely important as drug resistance continues to rise. It's crucial to have programs that oversee the use of antibiotics which can help reduce the emergence of resistance. Rapid diagnostic tools like polymerase chain reaction and next generation sequencing (PCR and NGS) are helpful in targeting treatment plans. Implementing rigorous infection control protocols can effectively reduce the transmission of infections, within healthcare facilities. Collaborative efforts between specialists ensure customized treatment plans that address resistance profiles. Combating evolving drug resistance involves approaches such as combination therapy and immunotherapies. Educating healthcare workers and patients about infection prevention and control is essential. Surveillance and epidemiology play a role in tracking resistance patterns, which in turn guide interventions. International cooperation is crucial due to travel patterns. Continuous research and innovation are essential for management providing insights into treatment effectiveness and mechanisms of resistance. The clinical implications of drug resistance such as increased severity, treatment failures and limited options underscore the need, for an approach. In conclusion, it is imperative to have clinical management strategies to tackle the challenges posed by emerging drug pathogens while safeguarding patient outcomes and public health.
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