通过多重基因组编辑 CRISPR 筛选揭示急性髓性白血病的治疗靶点

IF 4.6 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Zhen Tian, Stacia Octaviani, Jian Huang
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Unraveling therapeutic targets in acute myeloid leukemia through multiplexed genome editing CRISPR screening
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来源期刊
CiteScore
8.90
自引率
1.70%
发文量
58
审稿时长
3 months
期刊介绍: The journal evaluates molecules, signalling pathways, receptors and other therapeutic targets and their potential as candidates for drug development. Articles in this journal focus on the molecular level and early preclinical studies. Articles should not include clinical information including specific drugs and clinical trials. The Editors welcome: Reviews covering novel disease targets at the molecular level and information on early preclinical studies and their implications for future drug development. Articles should not include clinical information including specific drugs and clinical trials. Original research papers reporting results of target selection and validation studies and basic mechanism of action studies for investigative and marketed drugs. The audience consists of scientists, managers and decision makers in the pharmaceutical industry, academic researchers working in the field of molecular medicine and others closely involved in R&D.
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