Biomass-Derived Washable Composites for Accelerating the Healing of Infected Wounds (4/2023)

In this article number 10.1002/bmm2.12055, Fuhang Jiao, Wei Zhao and their co-workers developed a biomass-derived wound dressing exploiting the composite of water-soluble fish gelatin (FG) and antibacterial ZnO@silk fibroin (ZSF) microspheres. The ZSF microspheres serve as both germicide and hydrophile components, endowing the composite with excellent antimicrobial capacity and water solubility. The ZSF/FG composite can be easily removed from the wound using excess water, thereby preventing secondary damage. Additionally, the full-thickness skin wound model on infected mice demonstrated efficient wound closure and reduced inflammatory response. The ZSF/FG composite is expected a promising candidate as wound dressing for clinical therapy.