氯替诺昔康对正常人肾功能的影响。

Human toxicology Pub Date : 1989-01-01 DOI:10.1177/096032718900800110

S J Warrington, A Dawnay, A Johnston, S Saul, P Turner, H P Ferber

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引用次数: 4

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Chlortenoxicam and renal function of normal human volunteers.

new drug belonging to the oxicam class with a potency of about ten times that of piroxicam in standard animal models of inflammation and analgesia.2 Piroxicam causes nephrotoxicity in dogs, mice and rats, and there have been reports in man. 3,4 Nephrotoxicity was seen in one of six baboons receiving chlortenoxicam 0.5 mg kg-1 d-1 for 6 months, but no effects on renal function in man have yet been reported. The influence on renal function in man of chlor-

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Human toxicology

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