关于治疗限制对患有慢性疾病的贫困人口的影响:以同情透析为例

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Olga Bountali,Sila Çetinkaya,Vishal Ahuja
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引用次数: 0

摘要

我们分析了一个拥挤的医疗保健服务设置导致急诊治疗慢性疾病的定期基础。关注问题的一个突出例子是,在一家公共资助的安全网医院,由于经常有需要透析(又名同情透析)的无保险终末期肾病患者抵达,急诊室(ER)人满为患。不幸的是,对于资金不足的ESRD患者(如无证移民)来说,这是唯一的治疗选择,而且只有当患者的临床状况在强制性协议后被认为有生命危险时才可以使用,包括在急诊室进行初步筛查评估,这是医院行政部门和县政策规定和传达的。筛查评估后,所谓的治疗限制到位,一定比例的患者被送回家;因此,急诊室是一个筛选阶段。这样做的目的是控制系统负荷,从而通过限制服务(即透析)来控制由于潜在疾病的慢性性质而反复到达的病人的过度拥挤。为了更深入地了解潜在的意外后果,我们将问题设置建模为一个程式化的排队网络,其中经常到达和受限制的服务受制于急诊室的强制性筛选评估。我们获得了与网络特性相关的基本定量度量的解析表达式以及更复杂的性能度量。感兴趣的绩效指标包括传统的和新的问题特定指标,例如那些表明由于排斥和治疗延误而导致患者福利恶化的指标。我们确定了单独限制治疗可能减轻或导致严重拥堵和治疗延误的病例,从而影响系统运行和患者福利。我们提供的基本见解集中在强制性协议对网络特征以及传统的和特定于问题的性能度量的影响这一发现上,这一影响是重要的和违反直觉的。然而,通过我们的方法,影响是可以分析和/或数字量化的。总的来说,我们的定量结果表明,强制性协议背后的想法可能是幼稚的。这是因为该方法不一定能达到控制系统负载和过度拥挤的预期目的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On the Impact of Treatment Restrictions for the Indigent Suffering from a Chronic Disease: The Case of Compassionate Dialysis
We analyze a congested healthcare delivery setting resulting from emergency treatment of a chronic disease on a regular basis. A prominent example of the problem of interest is congestion in the emergency room (ER) at a publicly funded safety net hospital resulting from recurrent arrivals of uninsured end-stage renal disease patients needing dialysis (a.k.a. compassionate dialysis). Unfortunately, this is the only treatment option for un/under-funded patients (e.g., undocumented immigrants) with ESRD, and it is available only when the patient’s clinical condition is deemed as life-threatening after a mandatory protocol, including an initial screening assessment in the ER as dictated and communicated by hospital administration and county policy. After the screening assessment, the so-called treatment restrictions are in place, and a certain percentage of patients are sent back home; the ER, thus, serves as a screening stage. The intention here is to control system load and, hence, overcrowding via restricting service (i.e., dialysis) for recurrent arrivals as a result of the chronic nature of the underlying disease. In order to develop a deeper understanding of potential unintended consequences, we model the problem setting as a stylized queueing network with recurrent arrivals and restricted service subject to the mandatory screening assessment in the ER. We obtain analytical expressions of fundamental quantitative metrics related to network characteristics along with more sophisticated performance measures. The performance measures of interest include both traditional and new problem-specific metrics, such as those that are indicative of deterioration in patient welfare because of rejections and treatment delays. We identify cases for which treatment restrictions alone may alleviate or lead to severe congestion and treatment delays, thereby impacting both the system operation and patient welfare. The fundamental insight we offer is centered around the finding that the impact of mandatory protocol on network characteristics as well as traditional and problem-specific performance measures is nontrivial and counterintuitive. However, impact is analytically and/or numerically quantifiable via our approach. Overall, our quantitative results demonstrate that the thinking behind the mandatory protocol is potentially naive. This is because the approach does not necessarily serve its intended purpose of controlling system-load and overcrowding.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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