酶法合成手性中间体罗丁司他乙酯

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-11-16 DOI:10.1080/10242422.2023.2281874

Deepthi Pulivarthi, Rakesh Goparaju, Ravinder Reddy Patlolla, Vinaykumar Allam, Anjali Priya Naik Kethavath, Linga Banoth, Subba Reddy BV

引用次数: 0

摘要

酮还原酶被广泛用于还原前手性酮以制备手性醇。然而，手性Ir(III)催化剂已被用于k的不对称还原。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Enzymatic approach to the synthesis of chiral intermediate of Rodatristat ethyl

Ketoreductases are widely explored for the reduction of prochiral ketones for the preparation of chiral alcohols. Though, the chiral Ir(III) catalyst has been used for the asymmetric reduction of k...

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.