酶法合成手性中间体罗丁司他乙酯

IF 1.4 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biocatalysis and Biotransformation Pub Date : 2023-11-16 DOI:10.1080/10242422.2023.2281874

Deepthi Pulivarthi, Rakesh Goparaju, Ravinder Reddy Patlolla, Vinaykumar Allam, Anjali Priya Naik Kethavath, Linga Banoth, Subba Reddy BV

引用次数: 0

摘要

酮还原酶被广泛用于还原前手性酮以制备手性醇。然而，手性Ir(III)催化剂已被用于k的不对称还原。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Enzymatic approach to the synthesis of chiral intermediate of Rodatristat ethyl

Ketoreductases are widely explored for the reduction of prochiral ketones for the preparation of chiral alcohols. Though, the chiral Ir(III) catalyst has been used for the asymmetric reduction of k...

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来源期刊

Biocatalysis and Biotransformation 生物-生化与分子生物学

CiteScore

4.40

自引率

5.60%

发文量

审稿时长

3 months

期刊介绍： Biocatalysis and Biotransformation publishes high quality research on the application of biological catalysts for the synthesis, interconversion or degradation of chemical species. Papers are published in the areas of: Mechanistic principles Kinetics and thermodynamics of biocatalytic processes Chemical or genetic modification of biocatalysts Developments in biocatalyst''s immobilization Activity and stability of biocatalysts in non-aqueous and multi-phasic environments, including the design of large scale biocatalytic processes Biomimetic systems Environmental applications of biocatalysis Metabolic engineering Types of articles published are; full-length original research articles, reviews, short communications on the application of biotransformations, and preliminary reports of novel catalytic activities.