原发性青光眼犬在Ahmed瓣膜植入失败后行晶状体切除术和内激光光凝治疗的视力结果。

IF 1.7 4区 农林科学 Q2 VETERINARY SCIENCES
Veterinary ophthalmology Pub Date : 2025-03-01 Epub Date: 2023-12-07 DOI:10.1111/vop.13172
Bactelius Turicea, Christian L Munevar, Sydney G Edwards, Lana L Linton
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引用次数: 0

摘要

目的:回顾性评价原发性闭角型青光眼(PACG)犬在闭角型青光眼(AVG)失败后行Ahmed瓣膜性腺植入术(AVG)、晶状体切除术和内激光环光凝术(ECP)伴或不伴水泡切除的视力结果。程序:审查了2008年至2022年4月的医疗记录。所有入选患者均先行AVG。在瓣膜失效后,除泡切除外,还进行了晶状体切除- ecp。如果医学上有必要,还进行了额外的ECP和AVG置换手术。评估的主要结果包括6、12、24和36个月的视力保持、平均IOP降低和青光眼药物(口服和局部)的数量。结果:13例患者的14只眼纳入研究。女性居多(n = 9),男性居多(n = 4)。青光眼初次诊断的平均年龄为6.82岁。AVG和晶状体切除- ecp术后,分别有93%、84%、60%和48%的眼睛在1年、2年、3年和4年时保持视力。晶状体切除术- ecp术后2个月和6个月的平均眼压分别显著降低9.64 mmHg (p = 0.015)和9.71 mmHg (p = 0.016)。在12个月、24个月和36个月时,平均眼压分别降低了2.45、7.25和12.25 mmHg,差异无统计学意义。除24个月外,在所有评估时间点,青光眼药物的数量都显著减少。结论:AVG联合晶状体切除- ecp在长期维持视力、降低IOP和青光眼药物使用次数方面是成功的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vision outcomes in dogs with primary glaucoma surgically treated with lensectomy and endolaser cyclophotocoagulation after an Ahmed valve gonioimplantation failure.

Objective: The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.

Procedure: Medical records from 2008 to April 2022 were reviewed. All patients selected had an AVG performed first. Following valve failure, lensectomy-ECP was performed in addition to bleb resection as indicated. Additional ECP and AVG replacement surgeries were performed as deemed medically necessary. Main outcomes evaluated included vision preservation, average IOP reduction, and the number of glaucoma medications (both oral and topical) at 6, 12, 24, and 36 months.

Results: Fourteen eyes from 13 patients were included in the study. Females were predominant (n = 9) compared with males (n = 4). Mean age at initial glaucoma diagnosis was 6.82 years. Following AVG and lensectomy-ECP, vision was preserved in 93%, 84%, 60%, and 48% of eyes at 1, 2, 3, and 4 years respectively. Following lensectomy-ECP, there was a significant reduction in mean IOP of 9.64 mmHg (p = .015) and 9.71 mmHg (p = .016) at 2 and 6 months, respectively. There was a reduction in mean IOP of 2.45, 7.25, and 12.25 mmHg at 12, 24, and 36 months, respectively, which was not statistically significant. There was a significant decrease in the number of glaucoma medications at all evaluated time points except 24 months.

Conclusions: Combined AVG and lensectomy-ECP is successful in maintaining vision long term as well as decreasing IOP, and the number of glaucoma medications administered.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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