mTORC1信号激活的敏感性使组织具有再生能力。

IF 4 Q2 CELL & TISSUE ENGINEERING

Cell Regeneration Pub Date : 2023-12-07 DOI:10.1186/s13619-023-00183-6

Hanyu Dou, Jianzhou Li, Taomin Huang, Xiaolei Ding

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引用次数: 0

摘要

更好地了解不同物种的再生能力是如何以及为什么不同的，不仅将提供对再生过程的见解，而且对再生医学的发展和治疗程序的改进具有价值。在《自然》杂志最近的一篇文章中，Zhulyn等人发现了雷帕霉素复合体1 (mTORC1)信号传导机制靶的激活在增强动物组织再生能力中发挥的关键作用。

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The sensitivity of mTORC1 signaling activation renders tissue regenerative capacity.

A better understanding of how and why the regenerative capacity differs among species will not only provide insights into the regeneration process but also hold value for the development of regenerative medicine and the improvement of healing procedures. In a recent Nature article, Zhulyn et al. identify a critical role played by the activation of mechanistic target of rapamycin complex 1 (mTORC1) signaling in enhancing tissue regenerative capacity in animals.

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来源期刊

Cell Regeneration Biochemistry, Genetics and Molecular Biology-Cell Biology

CiteScore

5.80

自引率

0.00%

发文量

审稿时长

35 days

期刊介绍： Cell Regeneration aims to provide a worldwide platform for researches on stem cells and regenerative biology to develop basic science and to foster its clinical translation in medicine. Cell Regeneration welcomes reports on novel discoveries, theories, methods, technologies, and products in the field of stem cells and regenerative research, the journal is interested, but not limited to the following topics: ◎ Embryonic stem cells ◎ Induced pluripotent stem cells ◎ Tissue-specific stem cells ◎ Tissue or organ regeneration ◎ Methodology ◎ Biomaterials and regeneration ◎ Clinical translation or application in medicine