一例Antiresorptive-Naïve新加坡华人Graves病患者的持续性双侧非典型股骨骨折。

IF 0.6 Q4 ENDOCRINOLOGY & METABOLISM

Journal of the ASEAN Federation of Endocrine Societies Pub Date : 2023-01-01 Epub Date: 2023-08-30 DOI:10.15605/jafes.038.02.17

Kuan Swen Choo, Lily Mae Dacay, Le Roy Chong, Linsey Utami Gani

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引用次数: 0

摘要

非典型股骨骨折(AFFs)是罕见的不良反应，双膦酸盐治疗。我们报告一个不寻常的病例双侧骨干AFFs在antiresorptive-naïve新加坡华裔女性格雷夫斯病。患者表现为右侧完全性AFF需要手术固定，左侧持续性不完全性AFF持续4年以上。股骨弓形、股骨几何形状内翻和民族影响可能是af形成的原因。本病例可能为了解亚洲高危人群af的发病机制提供线索。

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Persistent Bilateral Atypical Femoral Fractures in an Antiresorptive-Naïve Singaporean Chinese Patient with Graves' Disease.

Atypical femoral fractures (AFFs) are rare adverse effects of bisphosphonate therapy. We report an unusual case of bilateral diaphyseal AFFs in an antiresorptive-naïve Singaporean Chinese female with Graves' disease. She presented with complete right AFF requiring surgical fixation, and persistent left incomplete AFF for over four years. Femoral bowing, varus femoral geometry, and ethnic influence likely contributed to the AFFs' formation. This case may provide insights into the pathogenesis of AFFs in high-risk Asian populations.

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来源期刊

Journal of the ASEAN Federation of Endocrine Societies ENDOCRINOLOGY & METABOLISM-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal of the ASEAN Federation of Endocrine Societies (JAFES) is an OPEN ACCESS, internationally peer-reviewed, English language, medical and health science journal that is published in print two times a year by the ASEAN Federation of Endocrine Societies. It shall serve as the endocrine window between the ASEAN region and the world, featuring original papers and publishing key findings from specialists and experts of endocrinology.