基于微模式的干细胞健身房:机械记忆增强的人牙髓干细胞干性维持和神经再生。板牙。49/2023)

IF 18.5 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Functional Materials Pub Date : 2023-12-01 DOI:10.1002/adfm.202370292

Chiyu Li, Fanqi Meng, Zhijie Yang, Jiang Peng, Yuwei Guo, Jing Na, Qiusheng Shi, Yu Liu, Yu Wang, Lisha Zheng, Yubo Fan

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引用次数: 0

摘要

干细胞健身房，王宇，郑丽莎，范玉波等人开发了一种基于微图案的干细胞健身房，用于训练牙髓干细胞的干细胞维持。以1024 μm2、1:2和1:4宽高比的微花纹体育馆为基础，可有效增强干细胞的干性，挽救干细胞在长期扩增过程中的多能性。干细胞运动诱导的机械记忆也能促进体内神经再生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Micropattern-Based Stem Cell Gym: Mechanical Memory Enhanced Stemness Maintenance of Human Dental Pulp Stem Cells and Nerve Regeneration (Adv. Funct. Mater. 49/2023)

查看原文本刊更多论文

Micropattern-Based Stem Cell Gym: Mechanical Memory Enhanced Stemness Maintenance of Human Dental Pulp Stem Cells and Nerve Regeneration (Adv. Funct. Mater. 49/2023)

Stem Cell Gym

In article number 2302829, Yu Wang, Lisha Zheng, Yubo Fan, and co-workers develop a micropatterned based stem cell gym to train dental pulp stem cells for stemness maintenance. The micropattern based gym with 1024 μm² and aspect ratios of 1:2 and 1:4 effectively enhances the stemness and rescues the pluripotency of stem cells during long-term expansion. The stem cell gym-induced mechanical memory also promotes nerve regeneration in vivo.

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来源期刊

Advanced Functional Materials 工程技术-材料科学：综合

CiteScore

29.50

自引率

4.20%

发文量

2086

审稿时长

2.1 months

期刊介绍： Firmly established as a top-tier materials science journal, Advanced Functional Materials reports breakthrough research in all aspects of materials science, including nanotechnology, chemistry, physics, and biology every week. Advanced Functional Materials is known for its rapid and fair peer review, quality content, and high impact, making it the first choice of the international materials science community.