不同波长激光同时应用于不同皮肤脱毛对细胞水平的影响:两例报告。

IF 1.2 4区 医学 Q3 DERMATOLOGY
Journal of Cosmetic and Laser Therapy Pub Date : 2023-11-17 Epub Date: 2023-11-30 DOI:10.1080/14764172.2023.2284640
Patrícia Froes Meyer, Rafaella Rêgo Maia, Rodrigo Marcel Valentim da Silva, Eneida de Morais Carreiro, Stephany Luanna Queiroga Farias, Dawson Henriques Malveira, Ciro Dantas Soares, Kelle Franciane Alves Soares, Graziele Maia Alves Serafim, Glenda Maria Correia de Oliveira, Cristina Mendes Silveira, Karla Maia Malveira, Brenda S Mansilla, Eduardo Pereira de Azevedo, Larissa Nobre de Melo
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引用次数: 0

摘要

本研究评估了不同波长的激光同时应用于不同皮肤的效果。样本包括两名参与者,一名是浅色皮肤,腹部有毛发的女性,另一名是深色皮肤,下肢内侧有毛发的女性,她们接受了激光治疗。术后45天行腹部成形术及大腿去皮手术。对照组毛囊处于生长期,有Bcl-2表达。在治疗区域,观察到毛囊处于晚期(休止期),CK-18的存在和Bcl-2的阴性,突出了此时的脱发阶段和研究毛囊的完全凋亡。生长期与休止期比较差异有统计学意义(p = .00),休止期与休止期比较差异有统计学意义(p = .00)。对照区生长期毛囊数量较多,治疗区休止期毛囊数量较多,说明不同波长激光在达到不同皮肤光型和毛发厚度时的效率,并被细胞凋亡和细胞增殖标记物强化。因此,使用不同波长的激光对脱毛工艺进行了优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects at cellular level of epilation with various laser wavelengths applied simultaneously on different skins: two case reports.

This study evaluated the effects of laser application of diverse wavelengths applied simultaneously and on different skins. The sample included two participants, a woman with light skin with abdominal hair and a woman with dark skin and hair on the inner part of the lower limbs, who received a laser therapy session. After 45 days from laser application, abdominoplasty and thigh dermolipectomy surgery were performed. In the control sample, the hair follicles were in the anagen phase, showing the presence of Bcl-2 expression. In the treated areas, follicles were observed in an advanced phase (telogen), with the presence of CK-18 and negativity of Bcl-2, highlighting the phase of hair loss at that moment and the complete apoptosis of the investigated follicle. Significant difference was observed in the comparison of the anagen phase (p = .00) and it similarly occurred in the comparison of the telogen phase (p = .00). The presence of a greater amount of follicles in the anagen phase in the control area and follicles in the telogen phase in the treated area demonstrates the efficiency of the laser at different wavelengths when reaching different skin phototypes and hair thickness, being reinforced by apoptosis and cell proliferation markers. Therefore, the hair-removal process has been optimized with various laser wavelengths.

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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues
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