内镜下乳头切除术对早期十二指肠壶腹癌患者有益吗?

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Ko Suzuki, Yusuke Kurita, Kensuke Kubota, Yuji Fujita, Seitaro Tsujino, Yuji Koyama, Shintaro Tsujikawa, Shigeki Tamura, Shin Yagi, Sho Hasegawa, Takamitsu Sato, Kunihiro Hosono, Noritoshi Kobayashi, Hiromichi Iwashita, Shoji Yamanaka, Satoshi Fujii, Itaru Endo, Atsushi Nakajima
{"title":"内镜下乳头切除术对早期十二指肠壶腹癌患者有益吗?","authors":"Ko Suzuki,&nbsp;Yusuke Kurita,&nbsp;Kensuke Kubota,&nbsp;Yuji Fujita,&nbsp;Seitaro Tsujino,&nbsp;Yuji Koyama,&nbsp;Shintaro Tsujikawa,&nbsp;Shigeki Tamura,&nbsp;Shin Yagi,&nbsp;Sho Hasegawa,&nbsp;Takamitsu Sato,&nbsp;Kunihiro Hosono,&nbsp;Noritoshi Kobayashi,&nbsp;Hiromichi Iwashita,&nbsp;Shoji Yamanaka,&nbsp;Satoshi Fujii,&nbsp;Itaru Endo,&nbsp;Atsushi Nakajima","doi":"10.1002/jhbp.1398","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background/Purpose</h3>\n \n <p>There is currently no consensus on the use of endoscopic papillectomy (EP) for early stage duodenal ampullary adenocarcinoma. This study aimed to evaluate the feasibility of EP for patients with early stage duodenal ampullary adenocarcinoma.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Patients who underwent EP for ampullary adenocarcinomas were investigated. Complete and clinical complete resection rates were evaluated. Clinical complete resection was defined as either complete resection or resection with positive or unknown margins but no cancer in the surgically resected specimen, or no recurrence on endoscopy after at least a 1-year follow-up.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Adenocarcinoma developed in 30 patients (carcinoma in situ [Tis]: 21, mucosal tumors [T1a(M)]: 4, tumors in the sphincter of Oddi [T1a(OD)]: 5). The complete resection rate was 60.0% (18/30) (Tis: 66.7% [14/21], T1a[M]: 50.0% [2/4], and T1a[OD]: 40.0% [2/5]). The mean follow-up period was 46.8 months. The recurrence rate for all patients was 6.7% (2/30). The clinical complete resection rates of adenocarcinoma were 89.2% (25/28); rates for Tis, T1a(M), and T1a(OD) were 89.4% (17/19), 100% (4/4), and 80% (4/5), respectively.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>EP may potentially achieve clinical complete resection of early stage (Tis and T1a) duodenal ampullary adenocarcinomas.</p>\n </section>\n </div>","PeriodicalId":16056,"journal":{"name":"Journal of Hepato‐Biliary‐Pancreatic Sciences","volume":null,"pages":null},"PeriodicalIF":3.2000,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Endoscopic papillectomy could be rewarding to patients with early stage duodenal ampullary carcinoma?\",\"authors\":\"Ko Suzuki,&nbsp;Yusuke Kurita,&nbsp;Kensuke Kubota,&nbsp;Yuji Fujita,&nbsp;Seitaro Tsujino,&nbsp;Yuji Koyama,&nbsp;Shintaro Tsujikawa,&nbsp;Shigeki Tamura,&nbsp;Shin Yagi,&nbsp;Sho Hasegawa,&nbsp;Takamitsu Sato,&nbsp;Kunihiro Hosono,&nbsp;Noritoshi Kobayashi,&nbsp;Hiromichi Iwashita,&nbsp;Shoji Yamanaka,&nbsp;Satoshi Fujii,&nbsp;Itaru Endo,&nbsp;Atsushi Nakajima\",\"doi\":\"10.1002/jhbp.1398\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background/Purpose</h3>\\n \\n <p>There is currently no consensus on the use of endoscopic papillectomy (EP) for early stage duodenal ampullary adenocarcinoma. This study aimed to evaluate the feasibility of EP for patients with early stage duodenal ampullary adenocarcinoma.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Patients who underwent EP for ampullary adenocarcinomas were investigated. Complete and clinical complete resection rates were evaluated. Clinical complete resection was defined as either complete resection or resection with positive or unknown margins but no cancer in the surgically resected specimen, or no recurrence on endoscopy after at least a 1-year follow-up.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Adenocarcinoma developed in 30 patients (carcinoma in situ [Tis]: 21, mucosal tumors [T1a(M)]: 4, tumors in the sphincter of Oddi [T1a(OD)]: 5). The complete resection rate was 60.0% (18/30) (Tis: 66.7% [14/21], T1a[M]: 50.0% [2/4], and T1a[OD]: 40.0% [2/5]). The mean follow-up period was 46.8 months. The recurrence rate for all patients was 6.7% (2/30). The clinical complete resection rates of adenocarcinoma were 89.2% (25/28); rates for Tis, T1a(M), and T1a(OD) were 89.4% (17/19), 100% (4/4), and 80% (4/5), respectively.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>EP may potentially achieve clinical complete resection of early stage (Tis and T1a) duodenal ampullary adenocarcinomas.</p>\\n </section>\\n </div>\",\"PeriodicalId\":16056,\"journal\":{\"name\":\"Journal of Hepato‐Biliary‐Pancreatic Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2023-11-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hepato‐Biliary‐Pancreatic Sciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jhbp.1398\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hepato‐Biliary‐Pancreatic Sciences","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jhbp.1398","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景/目的:目前对于早期十二指肠壶腹腺癌的内镜下乳头切除术(EP)的应用尚无共识。本研究旨在探讨早期十二指肠壶腹腺癌患者应用EP的可行性。方法:对壶腹腺癌行EP的患者进行分析。评估全切率和临床全切率。临床完全切除定义为完全切除或切除边缘阳性或未知,但手术切除标本中无癌,或至少1年随访后内窥镜检查未复发。结果:腺癌30例(原位癌[Tis]: 21例,粘膜肿瘤[T1a(M)]: 4例,Oddi括约肌肿瘤[T1a(OD)]: 5例),全切除率为60.0% (18/30)(Tis: 66.7% [14/21], T1a[M]: 50.0% [2/4], T1a[OD]: 40.0%[2/5])。平均随访46.8个月。所有患者复发率6.7%(2/30)。腺癌临床完全切除率为89.2% (25/28);Tis、T1a(M)和T1a(OD)的检出率分别为89.4%(17/19)、100%(4/4)和80%(4/5)。结论:EP有可能实现早期(Tis和T1a)十二指肠壶腹腺癌的临床完全切除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic papillectomy could be rewarding to patients with early stage duodenal ampullary carcinoma?

Background/Purpose

There is currently no consensus on the use of endoscopic papillectomy (EP) for early stage duodenal ampullary adenocarcinoma. This study aimed to evaluate the feasibility of EP for patients with early stage duodenal ampullary adenocarcinoma.

Methods

Patients who underwent EP for ampullary adenocarcinomas were investigated. Complete and clinical complete resection rates were evaluated. Clinical complete resection was defined as either complete resection or resection with positive or unknown margins but no cancer in the surgically resected specimen, or no recurrence on endoscopy after at least a 1-year follow-up.

Results

Adenocarcinoma developed in 30 patients (carcinoma in situ [Tis]: 21, mucosal tumors [T1a(M)]: 4, tumors in the sphincter of Oddi [T1a(OD)]: 5). The complete resection rate was 60.0% (18/30) (Tis: 66.7% [14/21], T1a[M]: 50.0% [2/4], and T1a[OD]: 40.0% [2/5]). The mean follow-up period was 46.8 months. The recurrence rate for all patients was 6.7% (2/30). The clinical complete resection rates of adenocarcinoma were 89.2% (25/28); rates for Tis, T1a(M), and T1a(OD) were 89.4% (17/19), 100% (4/4), and 80% (4/5), respectively.

Conclusions

EP may potentially achieve clinical complete resection of early stage (Tis and T1a) duodenal ampullary adenocarcinomas.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Hepato‐Biliary‐Pancreatic Sciences
Journal of Hepato‐Biliary‐Pancreatic Sciences GASTROENTEROLOGY & HEPATOLOGY-SURGERY
自引率
10.00%
发文量
178
审稿时长
6-12 weeks
期刊介绍: The Journal of Hepato-Biliary-Pancreatic Sciences (JHBPS) is the leading peer-reviewed journal in the field of hepato-biliary-pancreatic sciences. JHBPS publishes articles dealing with clinical research as well as translational research on all aspects of this field. Coverage includes Original Article, Review Article, Images of Interest, Rapid Communication and an announcement section. Letters to the Editor and comments on the journal’s policies or content are also included. JHBPS welcomes submissions from surgeons, physicians, endoscopists, radiologists, oncologists, and pathologists.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信