[抗原呈递受损作为肿瘤逃避免疫监视原因的分子机制]。

Q4 Medicine

Arkhiv patologii Pub Date : 2023-01-01 DOI:10.17116/patol20238506176

A A Korotaeva, A A Borunova, A Yu Kuzevanova, T N Zabotina, A A Alimov

{"title":"[抗原呈递受损作为肿瘤逃避免疫监视原因的分子机制]。","authors":"A A Korotaeva, A A Borunova, A Yu Kuzevanova, T N Zabotina, A A Alimov","doi":"10.17116/patol20238506176","DOIUrl":null,"url":null,"abstract":"The review summarizes data on the features of antigen presentation in tumor cells. The molecular mechanisms of the antitumor immune response are considered with an emphasis on the ability of tumor cells to avoid the action of immune surveillance. The features of expression of MHC molecules depending on treatment regimens are provided. Ways to improve existing and create new treatment regimens aimed at elimination of tumor cells because of antitumor immune response are discussed.","PeriodicalId":8548,"journal":{"name":"Arkhiv patologii","volume":"85 6","pages":"76-83"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Molecular mechanisms of impaired antigenic presentation as a cause of tumor escape from immune surveillance].\",\"authors\":\"A A Korotaeva, A A Borunova, A Yu Kuzevanova, T N Zabotina, A A Alimov\",\"doi\":\"10.17116/patol20238506176\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The review summarizes data on the features of antigen presentation in tumor cells. The molecular mechanisms of the antitumor immune response are considered with an emphasis on the ability of tumor cells to avoid the action of immune surveillance. The features of expression of MHC molecules depending on treatment regimens are provided. Ways to improve existing and create new treatment regimens aimed at elimination of tumor cells because of antitumor immune response are discussed.\",\"PeriodicalId\":8548,\"journal\":{\"name\":\"Arkhiv patologii\",\"volume\":\"85 6\",\"pages\":\"76-83\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arkhiv patologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17116/patol20238506176\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arkhiv patologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/patol20238506176","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

本文综述了肿瘤细胞中抗原递呈特征的研究资料。抗肿瘤免疫反应的分子机制被考虑，重点是肿瘤细胞避免免疫监视作用的能力。提供了MHC分子在不同治疗方案下的表达特征。讨论了改善现有治疗方案和创造新的治疗方案的方法，目的是消除肿瘤细胞，因为抗肿瘤免疫反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[Molecular mechanisms of impaired antigenic presentation as a cause of tumor escape from immune surveillance].

The review summarizes data on the features of antigen presentation in tumor cells. The molecular mechanisms of the antitumor immune response are considered with an emphasis on the ability of tumor cells to avoid the action of immune surveillance. The features of expression of MHC molecules depending on treatment regimens are provided. Ways to improve existing and create new treatment regimens aimed at elimination of tumor cells because of antitumor immune response are discussed.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Arkhiv patologii Medicine-Pathology and Forensic Medicine

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.