口语干预可以改善神经发育障碍儿童的语言预后:一项系统回顾和荟萃分析

IF 4 Q1 SOCIAL SCIENCES, INTERDISCIPLINARY
Enrica Donolato, Enrico Toffalini, Kristin Rogde, Anders Nordahl-Hansen, Arne Lervåg, Courtenay Norbury, Monica Melby-Lervåg
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引用次数: 0

摘要

没有像预期那样发展语言的年轻人在生活的各个方面都面临着巨大的挑战。不幸的是,语言障碍很常见,要么作为一种独特的疾病(例如,发展性语言障碍),要么作为另一种神经发育疾病(例如,自闭症)的一部分。通过干预找到减轻语言问题的方法不仅对个人而且对整个社会都有很大的好处。目的:本荟萃分析综述了口头语言干预对神经发育障碍儿童的影响。最后一次电子检索是在2022年4月。干预研究必须在随机对照试验或准实验设计中针对2至18岁患有发展性语言障碍、自闭症、智力残疾、唐氏综合征、脆性X染色体综合征和威廉姆斯综合征的儿童的语言技能。对照组必须包括一切照旧、等候名单、被动或主动的情况。然而,我们排除了积极对照组接受不同类型、递送或剂量的另一种语言干预的研究。合格的干预措施实施明确的和结构化的活动(即,明确的词汇,叙事结构或语法规则的指导)和/或隐含的和广泛的活动(即,共同阅读书籍,一般的语言刺激)。干预研究必须评估语言技能的接受和/或表达方式。数据采集与分析重复数据删除后,查询得到8195条记录。通过题目和摘要对记录进行筛选,对448条记录进行全文检索。我们进行了相关和层次效应模型,并通过模拟进行了回顾性功率分析。通过p曲线和精度效应估计评估发表偏倚。我们检查了38项研究,其中46项组比较,108项比较测试前后的影响;8项研究,12项组比较,21项随访影响。结果显示,后测时平均效应量d = 0.27,随访时平均效应量d = 0.18。然而,有证据表明存在发表偏倚和对平均效应的高估。元分析结果表明:(1)相对于表达性词汇、语法、表达性话语和接受性话语以及综合表达性测试,接受性词汇和综合接受性测试的效果较小;(2)干预的长度,在较长的时间内进行较长的治疗比短暂的治疗和短期干预更有益。受试者特征(儿童诊断、诊断状态、年龄、性别、非言语认知能力和语言障碍严重程度)、治疗成分和语言干预实施(干预内容、设置、交付代理人、干预的会话结构或总会话数)的调节因子均未达到显著性。研究质量的指标也出现了同样的情况。偏倚风险评估显示,本综述中研究的报告质量较差。总之,目前的证据基础是有希望的,但不确定。为了推动循证实践和政策,需要对包括更广泛的诊断条件在内的更可靠、更有力的试验进行预注册和复制,并进行更长期的随访比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Oral language interventions can improve language outcomes in children with neurodevelopmental disorders: A systematic review and meta-analysis

Oral language interventions can improve language outcomes in children with neurodevelopmental disorders: A systematic review and meta-analysis

Background

Young people who fail to develop language as expected face significant challenges in all aspects of life. Unfortunately, language disorders are common, either as a distinct condition (e.g., Developmental Language Disorder) or as a part of another neurodevelopmental condition (e.g., autism). Finding ways to attenuate language problems through intervention has the potential to yield great benefits not only for the individual but also for society as a whole.

Objectives

This meta-analytic review examined the effect of oral language interventions for children with neurodevelopmental disorders.

Search Methods

The last electronic search was conducted in April 2022.

Selection Criteria

Intervention studies had to target language skills for children from 2 to 18 years of age with Developmental Language Disorder, autism, intellectual disability, Down syndrome, Fragile X syndrome, and Williams syndrome in randomised controlled trials or quasi-experimental designs. Control groups had to include business-as-usual, waiting list, passive or active conditions. However, we excluded studies in which the active control group received a different type, delivery, or dosage of another language intervention. Eligible interventions implemented explicit and structured activities (i.e., explicit instruction of vocabulary, narrative structure or grammatical rules) and/or implicit and broad activities (i.e., shared book reading, general language stimulation). The intervention studies had to assess language skills in receptive and/or expressive modalities.

Data Collection and Analysis

The search provided 8195 records after deduplication. Records were screened by title and abstract, leading to full-text examinations of 448 records. We performed Correlated and Hierarchical Effects models and ran a retrospective power analysis via simulation. Publication bias was assessed via p-curve and precision-effect estimate.

Main Results

We examined 38 studies, with 46 group comparisons and 108 effects comparing pre-/post-tests and eight studies, with 12 group comparisons and 21 effects at follow-up. The results showed a mean effect size of d = 0.27 at the post-test and d = 0.18 at follow-up. However, there was evidence of publication bias and overestimation of the mean effects. Effects from the meta-analysis were significantly related to these elements: (1) receptive vocabulary and omnibus receptive measures showed smaller effect sizes relative to expressive vocabulary, grammar, expressive and receptive discourse, and omnibus expressive tests; and (2) the length of the intervention, where longer sessions conducted over a longer period of time were more beneficial than brief sessions and short-term interventions. Neither moderators concerning participants’ characteristics (children's diagnosis, diagnostic status, age, sex, and non-verbal cognitive ability and severity of language impairment), nor those regarding of the treatment components and implementation of the language interventions (intervention content, setting, delivery agent, session structure of the intervention or total number of sessions) reached significance. The same occurred to indicators of study quality. The risk of bias assessment showed that reporting quality for the studies examined in the review was poor.

Authors’ Conclusions

In sum, the current evidence base is promising but inconclusive. Pre-registration and replication of more robust and adequately powered trials, which include a wider range of diagnostic conditions, together with more long-term follow-up comparisons, are needed to drive evidence-based practice and policy.

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来源期刊
Campbell Systematic Reviews
Campbell Systematic Reviews Social Sciences-Social Sciences (all)
CiteScore
5.50
自引率
21.90%
发文量
80
审稿时长
6 weeks
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