使用PRF、CGF和自体骨治疗牙周骨内缺损的临床和影像学评价:使用自体产品治疗牙周缺损

IF 4.2 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Basem Alshujaa, Ahmet Cemil Talmac, Dicle Altindal, Anas Alsafadi, Abdullah Seckin Ertugrul
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引用次数: 0

摘要

背景:本随机临床研究的目的是临床评价和比较富血小板纤维蛋白(PRF)、浓缩生长因子(CGF)和自体骨移植(ABG)治疗骨内袋的效果,并评估牙槽骨增重(AB增重)x线摄影(全景和CBCT图像)。方法:将80个骨内袋分为4组:单纯开瓣清创(OFD)组、OFD+PRF组、OFD+CGF组和OFD+ABG组;每组有20个缺陷。采用Periotest M器械评估牙菌斑指数(PI)、牙龈指数(GI)、探探深度(PD)、临床附着水平(CAL)和牙齿活动度(TM)。x线图像也被用来评估AB增益。在2700转/分(RPM) 12分钟的转速下产生PRF,并评估相对离心力(RCF)。CGF的制备方法为:2 min 2700 rpm, 4 min 2400 rpm, 4 min 2700 rpm, 3 min 3000 rpm。结果:研究结果显示,各组PI和GI值的改善相似(p < 0.05)。与其他组相比,ABG组在180天PD和CAL下降有统计学意义(p = 0.001)。TM和牙槽骨高度损失(ABHL)也有统计学意义的降低,其中AB增加在各组间逐渐增加,ABG组最好,CGF组次之,PRF组次之,对照组次之(p = 0.001)。结论:本研究结果支持OFD联合ABG、CGF和PRF治疗牙周骨内袋,ABG效果最好,CGF和PRF效果次之。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical and radiographic evaluation of the use of PRF, CGF, and autogenous bone in the treatment of periodontal intrabony defects: Treatment of periodontal defect by using autologous products

Background

The purpose of this randomized clinical study was to clinically evaluate and compare the efficiencies of platelet-rich fibrin (PRF), concentrated growth factor (CGF) and autogenous bone graft (ABG) in the treatment of intrabony pockets and to assess the alveolar bone gain (AB gain) radiographically (panoramic and CBCT images).

Methods

Eighty intrabony pockets were divided into four groups: ojnly open flap debridement (OFD), OFD+PRF, OFD+CGF and OFD+ABG; each group consisted of 20 defects. Plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), and tooth mobility (TM) by using Periotest M device were evaluated. Radiographic images were also taken to evaluate the AB gain. PRF was produced using a protocol of 2,700 RPM for 12 min and the relative centrifugal force (RCF) was evaluated. CGF was prepared as follows: 2 min 2700 rpm, 4 min 2400 rpm, 4 min 2700 rpm, 3 min 3000 rpm.

Results

The study results revealed a similar improvement in PI and GI values in all groups (p > 0.05). There was a statistically significant decrease in PD and CAL in favor of ABG group at day 180 in comparison with other groups (p = 0.001). There was also a statistically significant decrease in TM and alveolar bone height loss (ABHL), whereby the AB gain gradually increased among the groups with the best group being ABG, followed by CGF, PRF, and control groups, respectively (p = 0.001).

Conclusions

The study results support the treatment of periodontal intrabony pockets using OFD in combination with ABG, CGF, and PRF, as ABG showed the best results followed by CGF and PRF.

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来源期刊
Journal of periodontology
Journal of periodontology 医学-牙科与口腔外科
CiteScore
9.10
自引率
7.00%
发文量
290
审稿时长
3-8 weeks
期刊介绍: The Journal of Periodontology publishes articles relevant to the science and practice of periodontics and related areas.
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