1,2-二甲基肼对小鼠肿瘤的诱导作用。

K Fujii, H Komano
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引用次数: 0

摘要

给新生ICR小鼠皮下注射1,2-二甲基肼,观察1年。诱导肺、肝肿瘤、恶性淋巴瘤等肿瘤。给予DMH 30 mg/kg体重的小鼠中,有2只小鼠发生结肠肿瘤,且结肠肿瘤发生率低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tumor induction in mice administered neonatally with 1,2-dimethylhydrazine.

1,2-Dimethylhydrazine was given subcutaneously to neonatal ICR mice, and animals were observed for one year. The tumors of lung and liver, malignant lymphoma, and other tumors were induced. In the mice given DMH 30 mg/kg of body weight, two mice developed colonic tumor, and the incidence of colonic tumor was low.

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