{"title":"香豆素(1,2-苯并吡喃酮)治疗患者肝毒性的罕见性。","authors":"D Cox, R O'Kennedy, R D Thornes","doi":"10.1177/096032718900800612","DOIUrl":null,"url":null,"abstract":"<p><p>1. Two thousand, one hundred and seventy-three patients with cancer or chronic infections were treated with coumarin in a clinical trial. 2. 0.37% of these patients developed elevated liver enzyme levels during therapy with coumarin. 3. This hepatitis was probably a form of idiosyncratic hepatotoxicity and may have been immune in origin.</p>","PeriodicalId":13194,"journal":{"name":"Human toxicology","volume":"8 6","pages":"501-6"},"PeriodicalIF":0.0000,"publicationDate":"1989-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/096032718900800612","citationCount":"101","resultStr":"{\"title\":\"The rarity of liver toxicity in patients treated with coumarin (1,2-benzopyrone).\",\"authors\":\"D Cox, R O'Kennedy, R D Thornes\",\"doi\":\"10.1177/096032718900800612\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>1. Two thousand, one hundred and seventy-three patients with cancer or chronic infections were treated with coumarin in a clinical trial. 2. 0.37% of these patients developed elevated liver enzyme levels during therapy with coumarin. 3. This hepatitis was probably a form of idiosyncratic hepatotoxicity and may have been immune in origin.</p>\",\"PeriodicalId\":13194,\"journal\":{\"name\":\"Human toxicology\",\"volume\":\"8 6\",\"pages\":\"501-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1177/096032718900800612\",\"citationCount\":\"101\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Human toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/096032718900800612\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/096032718900800612","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The rarity of liver toxicity in patients treated with coumarin (1,2-benzopyrone).
1. Two thousand, one hundred and seventy-three patients with cancer or chronic infections were treated with coumarin in a clinical trial. 2. 0.37% of these patients developed elevated liver enzyme levels during therapy with coumarin. 3. This hepatitis was probably a form of idiosyncratic hepatotoxicity and may have been immune in origin.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
