{"title":"[大鼠离体血灌注肺缺氧血管收缩实验模型]。","authors":"R Brandt, A Oddoy, J Böhnke, W Schilling","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Comparing two variants of models (in situ, ex situ) of the isolated blood-perfused rat lung for measurement of the hypoxic pulmonary vasoconstriction the in situ preparation gave better results. The optimal severity of hypoxia was 2% O2 in intervals (hypoxia and normoxia, respectively) of seven minutes. The model works sufficiently for two hours.</p>","PeriodicalId":76840,"journal":{"name":"Zeitschrift fur Erkrankungen der Atmungsorgane","volume":"173 2","pages":"145-50"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[A model of the isolated blood perfused lung of rats in testing hypoxic pulmonary vasoconstriction].\",\"authors\":\"R Brandt, A Oddoy, J Böhnke, W Schilling\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Comparing two variants of models (in situ, ex situ) of the isolated blood-perfused rat lung for measurement of the hypoxic pulmonary vasoconstriction the in situ preparation gave better results. The optimal severity of hypoxia was 2% O2 in intervals (hypoxia and normoxia, respectively) of seven minutes. The model works sufficiently for two hours.</p>\",\"PeriodicalId\":76840,\"journal\":{\"name\":\"Zeitschrift fur Erkrankungen der Atmungsorgane\",\"volume\":\"173 2\",\"pages\":\"145-50\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Erkrankungen der Atmungsorgane\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Erkrankungen der Atmungsorgane","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[A model of the isolated blood perfused lung of rats in testing hypoxic pulmonary vasoconstriction].
Comparing two variants of models (in situ, ex situ) of the isolated blood-perfused rat lung for measurement of the hypoxic pulmonary vasoconstriction the in situ preparation gave better results. The optimal severity of hypoxia was 2% O2 in intervals (hypoxia and normoxia, respectively) of seven minutes. The model works sufficiently for two hours.
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