{"title":"隐球菌性肺炎1例假阳性[18F]氟-2-脱氧-d-葡萄糖正电子发射断层扫描(FDG-PET)图像模拟肺转移癌","authors":"Cheng Ji , Chunhua Ling , Bin Zhang , Haodong Xu","doi":"10.1016/j.rmedc.2009.04.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>There is an increasing use of positron emission tomography with [<sup>18</sup>F]fluoro-2-deoxy-<span>d</span>-glucose (FDG-PET) for differential diagnosis between lung malignancy and other pulmonary diseases such as infection. However, false-positive FDG-PET images mimicking lung cancer can occur in pulmonary infection.</p></div><div><h3>Objective</h3><p>This study was to describe a case of cryptococcal pneumonia with false-positive FDG-PET image mimicking metastatic lung cancer.</p></div><div><h3>Patient and results</h3><p>We analyzed the clinical features and chest CT and FDG-PET characteristics of a case of pulmonary cryptococcosis that was initially suspected to have lung metastasis of gastric cancer and treated by surgery. During a follow-up, the 49 years old, female patient with a 7-year history of gastric adenocarcinoma showed a 1.0-cm nodule in the right lower lobe of lung on her chest CT scan with an accumulation of FDG (SUV<!--> <!-->=<!--> <!-->4.5) on her PET image. With a clinical diagnosis of suspected lung metastatic cancer, the lung wedge resection was then performed. Histological analysis of the resected nodule confirmed a diagnosis of cryptococcal pneumonia.</p></div><div><h3>Conclusion</h3><p>The FDG-PET image is not particularly helpful in segregating pulmonary infection from lung malignancy in certain cases. Surgical resection is recommended for both diagnosis and treatment of pulmonary cryptococcosis.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"3 2","pages":"Pages 93-94"},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2009.04.005","citationCount":"0","resultStr":"{\"title\":\"A case of cryptococcal pneumonia with false-positive [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) image mimicking lung metastatic cancer\",\"authors\":\"Cheng Ji , Chunhua Ling , Bin Zhang , Haodong Xu\",\"doi\":\"10.1016/j.rmedc.2009.04.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>There is an increasing use of positron emission tomography with [<sup>18</sup>F]fluoro-2-deoxy-<span>d</span>-glucose (FDG-PET) for differential diagnosis between lung malignancy and other pulmonary diseases such as infection. However, false-positive FDG-PET images mimicking lung cancer can occur in pulmonary infection.</p></div><div><h3>Objective</h3><p>This study was to describe a case of cryptococcal pneumonia with false-positive FDG-PET image mimicking metastatic lung cancer.</p></div><div><h3>Patient and results</h3><p>We analyzed the clinical features and chest CT and FDG-PET characteristics of a case of pulmonary cryptococcosis that was initially suspected to have lung metastasis of gastric cancer and treated by surgery. During a follow-up, the 49 years old, female patient with a 7-year history of gastric adenocarcinoma showed a 1.0-cm nodule in the right lower lobe of lung on her chest CT scan with an accumulation of FDG (SUV<!--> <!-->=<!--> <!-->4.5) on her PET image. With a clinical diagnosis of suspected lung metastatic cancer, the lung wedge resection was then performed. Histological analysis of the resected nodule confirmed a diagnosis of cryptococcal pneumonia.</p></div><div><h3>Conclusion</h3><p>The FDG-PET image is not particularly helpful in segregating pulmonary infection from lung malignancy in certain cases. Surgical resection is recommended for both diagnosis and treatment of pulmonary cryptococcosis.</p></div>\",\"PeriodicalId\":89478,\"journal\":{\"name\":\"Respiratory medicine CME\",\"volume\":\"3 2\",\"pages\":\"Pages 93-94\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.rmedc.2009.04.005\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respiratory medicine CME\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1755001709000475\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiratory medicine CME","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1755001709000475","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A case of cryptococcal pneumonia with false-positive [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) image mimicking lung metastatic cancer
Background
There is an increasing use of positron emission tomography with [18F]fluoro-2-deoxy-d-glucose (FDG-PET) for differential diagnosis between lung malignancy and other pulmonary diseases such as infection. However, false-positive FDG-PET images mimicking lung cancer can occur in pulmonary infection.
Objective
This study was to describe a case of cryptococcal pneumonia with false-positive FDG-PET image mimicking metastatic lung cancer.
Patient and results
We analyzed the clinical features and chest CT and FDG-PET characteristics of a case of pulmonary cryptococcosis that was initially suspected to have lung metastasis of gastric cancer and treated by surgery. During a follow-up, the 49 years old, female patient with a 7-year history of gastric adenocarcinoma showed a 1.0-cm nodule in the right lower lobe of lung on her chest CT scan with an accumulation of FDG (SUV = 4.5) on her PET image. With a clinical diagnosis of suspected lung metastatic cancer, the lung wedge resection was then performed. Histological analysis of the resected nodule confirmed a diagnosis of cryptococcal pneumonia.
Conclusion
The FDG-PET image is not particularly helpful in segregating pulmonary infection from lung malignancy in certain cases. Surgical resection is recommended for both diagnosis and treatment of pulmonary cryptococcosis.
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