Marlos Melo Martins , Arnaldo Prata‐Barbosa , Antonio José Ledo Alves da Cunha
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These diseases remain a major public health challenge, due to the lack of specific antiviral treatment, the co‐circulation of different arboviruses in endemic/epidemic regions, the lack of effective and safe immunizations for the vast majority of these viruses, and the great difficulty in vector control, especially in large urban centers.</p></div><div><h3>Conclusions</h3><p>Children are especially vulnerable to this group of diseases due to characteristics that facilitate the development of the most severe forms. More detailed knowledge of this group of diseases allows the pediatrician to diagnose them earlier, implement the correct treatment, monitor warning signs for the most severe forms, and establish effective preventive measures.</p></div>","PeriodicalId":100742,"journal":{"name":"Jornal de Pediatria (Vers?o em Português)","volume":"96 ","pages":"Pages 2-11"},"PeriodicalIF":0.0000,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.006","citationCount":"0","resultStr":"{\"title\":\"Arboviral diseases in pediatrics\",\"authors\":\"Marlos Melo Martins , Arnaldo Prata‐Barbosa , Antonio José Ledo Alves da Cunha\",\"doi\":\"10.1016/j.jpedp.2019.08.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>To present the currently available evidence on transmission, clinical, diagnostic methods, treatment, and prevention methods of major arboviruses that occur in childhood.</p></div><div><h3>Source of data</h3><p>Non‐systematic review carried out in MEDLINE (PubMed), LILACS (VHL), Scopus, Web of Science, Cochrane, CAPES Portal, and Google Scholar databases for the past five years using the search terms arboviruses, dengue, chikungunya, Zika, Mayaro, and West Nile fever, as well as child, newborn, and adolescent.</p></div><div><h3>Synthesis of data</h3><p>The main characteristic of arboviruses is the fact that part of their replication cycle occurs inside insect vectors, thus being classically transmitted to humans through the bite of mosquitoes (hematophagous arthropods), although non‐vector transmission of these viruses is also possible in specific situations. These diseases remain a major public health challenge, due to the lack of specific antiviral treatment, the co‐circulation of different arboviruses in endemic/epidemic regions, the lack of effective and safe immunizations for the vast majority of these viruses, and the great difficulty in vector control, especially in large urban centers.</p></div><div><h3>Conclusions</h3><p>Children are especially vulnerable to this group of diseases due to characteristics that facilitate the development of the most severe forms. More detailed knowledge of this group of diseases allows the pediatrician to diagnose them earlier, implement the correct treatment, monitor warning signs for the most severe forms, and establish effective preventive measures.</p></div>\",\"PeriodicalId\":100742,\"journal\":{\"name\":\"Jornal de Pediatria (Vers?o em Português)\",\"volume\":\"96 \",\"pages\":\"Pages 2-11\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jpedp.2019.08.006\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jornal de Pediatria (Vers?o em Português)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2255553619301739\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jornal de Pediatria (Vers?o em Português)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2255553619301739","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的介绍儿童主要虫媒病毒的传播、临床、诊断方法、治疗和预防方法。资料来源:在MEDLINE (PubMed)、LILACS (VHL)、Scopus、Web of Science、Cochrane、CAPES Portal和Google Scholar数据库中对过去5年进行了系统综述,检索词为虫媒病毒、登革热、基孔肯雅热、寨卡病毒、马亚罗病毒和西尼罗热,以及儿童、新生儿和青少年。虫媒病毒的主要特征是其部分复制周期发生在昆虫媒介内部,因此通常通过蚊子(食血节肢动物)的叮咬传播给人类,尽管在特定情况下这些病毒也可能通过非媒介传播。由于缺乏特异性抗病毒治疗,不同虫媒病毒在流行地区共循环,对绝大多数病毒缺乏有效和安全的免疫接种,以及病媒控制困难重重,特别是在大城市中心,这些疾病仍然是一项重大的公共卫生挑战。结论儿童易患这类疾病,其特点是易发展为最严重的形式。对这组疾病的更详细的了解使儿科医生能够更早地诊断它们,实施正确的治疗,监测最严重形式的警告信号,并建立有效的预防措施。
To present the currently available evidence on transmission, clinical, diagnostic methods, treatment, and prevention methods of major arboviruses that occur in childhood.
Source of data
Non‐systematic review carried out in MEDLINE (PubMed), LILACS (VHL), Scopus, Web of Science, Cochrane, CAPES Portal, and Google Scholar databases for the past five years using the search terms arboviruses, dengue, chikungunya, Zika, Mayaro, and West Nile fever, as well as child, newborn, and adolescent.
Synthesis of data
The main characteristic of arboviruses is the fact that part of their replication cycle occurs inside insect vectors, thus being classically transmitted to humans through the bite of mosquitoes (hematophagous arthropods), although non‐vector transmission of these viruses is also possible in specific situations. These diseases remain a major public health challenge, due to the lack of specific antiviral treatment, the co‐circulation of different arboviruses in endemic/epidemic regions, the lack of effective and safe immunizations for the vast majority of these viruses, and the great difficulty in vector control, especially in large urban centers.
Conclusions
Children are especially vulnerable to this group of diseases due to characteristics that facilitate the development of the most severe forms. More detailed knowledge of this group of diseases allows the pediatrician to diagnose them earlier, implement the correct treatment, monitor warning signs for the most severe forms, and establish effective preventive measures.