儿科骨关节感染

Paula Andrade Alvares , Marcelo Jenné Mimica
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引用次数: 0

摘要

目的收集有关儿童骨关节感染的最新信息,包括流行病学和微生物学特征、诊断和治疗。在PubMed、SciELO、Lilacs和b谷歌Scholar等搜索引擎上进行了一项非系统综述,检索关键词为“骨和关节感染”、“儿童”、“儿科”、“骨髓炎”、“化脓性关节炎”和“脊椎椎间盘炎”,检索时间为近十年。作者选取最相关的文章组成数据库。骨关节感染仍然是儿科发病率的主要原因。它们的主要病因是金黄色葡萄球菌,但金氏菌的检测有所增加,特别是通过分子方法。微生物鉴定可以指导治疗方向,而炎症活动的证据有助于治疗随访。影像学检查在感染的初步诊断中特别有用。经验性治疗应根据患者的年龄和临床情况对主要微生物进行覆盖,同时考虑到当地的耐药情况。外科手术可用于诊断、病灶控制和功能保存。急性并发症包括败血症、深静脉血栓和肺栓塞。死亡人数很少。晚期并发症并不常见,但可能导致损害运动发育的畸形。结论正确、早期诊断、及时实施适当的抗菌药物治疗和病灶控制是改善预后的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Osteoarticular infections in pediatrics

Objective

To collect the most up‐to‐date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment.

Source of data

A non‐systematic review was performed on the search engines PubMed, SciELO, Lilacs, and Google Scholar, using the keywords “bone and joint infection”, “children”, “pediatric”, “osteomyelitis”, “septic arthritis” and “spondylodiscitis” over the last ten years. The most relevant articles were selected by the authors to constitute the database.

Synthesis of data

Osteoarticular infections are still a major cause of morbidity in pediatrics. Their main etiology is Staphylococcus aureus, but there has been an increase in the detection of Kingella kingae, especially through molecular methods. Microbiological identification allows treatment direction, while evidence of inflammatory activity assists in treatment follow‐up. Imaging tests are especially useful in the initial diagnosis of infections. Empirical treatment should include coverage for the main microorganisms according to the age and clinical conditions of the patient, while considering the local resistance profile. Surgical procedures can be indicated for diagnosis, focus control, and function preservation. Acute complications include sepsis, deep venous thrombosis, and pulmonary embolism. Deaths are rare. Late complications are uncommon but may lead to deformities that compromise motor development.

Conclusion

A correct and early diagnosis, prompt implementation of adequate antimicrobial therapy, and focus control, when indicated, are critical to a better prognosis.

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