[哥伦比亚猴痘患者的流行病学特征及其与住院事件的关系]。

Revista espanola de salud publica Pub Date : 2023-11-17
Jorge Homero Wilches-Visbal, Hugo Luis Sánchez-González, Midian Clara Castillo-Pedraza
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引用次数: 0

摘要

目的:自2022年初以来,在非流行国家发生了一次不寻常的猴痘疫情,引起了国际社会的警惕。在哥伦比亚,最近没有对这种新流行病患者的流行病学进行研究。因此,本文的目的是建立猴痘患者的人口学和临床特征,以及它们与住院次数和其他临床报告变量的关系。方法:对2022年5月至9月期间哥伦比亚猴痘病例进行观察性、分析性和横断面研究。采用Mann-Whitney U检验比较住院率与社会人口学和定量通知变量之间的假设;采用费雪精确检验与定性检验进行对比。结果:2022年5月至9月,哥伦比亚共报告猴痘1260例,其中75%在波哥大登记,99%(1248例)感染者为男性,中位年龄为32.82%,患者来自第二和第三阶层(低收入至中低收入)。超过80%的病例感染源不明。只有不到1%的人属于少数民族。只有3%需要住院治疗。在住院频率、女性(p=0.038)、非裔哥伦比亚人(p=0.024)和补贴制度(p=0.009)之间发现了显著的统计学关联。住院与年龄无关,但与从出现症状/皮疹到通知/诊断的天数有关(结论:猴痘病例集中在首都和哥伦比亚其他安第斯省)。大多数的进展都不严重,没有死亡。男性是受影响最大的人群。妇女、非裔哥伦比亚人和得到补贴的病人值得特别关注,因为她们更容易住院。减少从症状或皮疹到诊断和通报的天数是避免严重病例的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Características epidemiológicas de pacientes con viruela símica y su relación con eventos de hospitalización en Colombia].

Objective: Since the beginning of 2022, there has been an unusual outbreak of monkeypox in non-endemic countries that has alerted the international community. In Colombia, there are no recent studies on the epidemiology of patients in this new epidemic. Therefore, aim of this article was to establish the demographic and clinical characteristics of patients with monkeypox and their relationship with the frequency of hospitalization and other variables of clinical notification.

Methods: An observational, analytical, and cross-sectional study on monkeypox cases in Colombia between May and September 2022 was executed. Mann-Whitney U test was applied to contrast hypotheses between hospitalization and sociodemographic and quantitative notification variables; Fisher's exact test was used to contrast with the qualitative ones.

Results: Between May and September 2022, there were 1,260 cases of monkeypox reported in Colombia, 75% of the these were registered in Bogotá D.C. 99% (1,248) of those infected were male with a median age of 32.82% of the patients were from strata 2 and 3 (low to medium-low income). The source of infection was unknown in just over 80% of cases. Less than 1% belonged to ethnic groups. Only 3% required hospitalization. A significant statistically association was found between the frequency of hospitalization, being a woman (p=0.038), Afro-Colombian (p=0.024) and subsidized regime (p=0.009). No association of hospitalization was found with age, but it was found with the days from the onset of symptoms/rash to notification/diagnosis (p<0.05).

Conclusions: Monkeypox cases are concentrated in the capital and other Andean departments of Colombia. Most of these progress without seriousness, without deaths. Men are the most affected population group. Women, afro-colombians and subsidized patients deserve special attention because they are more prone to hospitalization. Reducing the number of days from symptoms or rash to diagnosis and notification is key to avoiding serious cases.

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