【医学真菌学临床问题:第56题】

IF 1.5 4区 生物学 Q4 MYCOLOGY
Fernando Messina , Emmanuel Marin , Alejandro Sansostera , Mercedes Romero , Roxana Depardo , Ricardo Negroni , Blanca Leonel , Gabriela Santiso
{"title":"【医学真菌学临床问题:第56题】","authors":"Fernando Messina ,&nbsp;Emmanuel Marin ,&nbsp;Alejandro Sansostera ,&nbsp;Mercedes Romero ,&nbsp;Roxana Depardo ,&nbsp;Ricardo Negroni ,&nbsp;Blanca Leonel ,&nbsp;Gabriela Santiso","doi":"10.1016/j.riam.2022.12.001","DOIUrl":null,"url":null,"abstract":"<div><p>We present the case of a twenty six year-old woman with rheumatoid arthritis, treated with certolizumab. She sought medical attention due to cough, fever and night sweats. X-ray exam showed a miliary pneumonia. She was treated for tuberculosis and 50<!--> <!-->days later she presented with aphasia. Magnetic nuclear resonance revealed brain lesions. <em>Histoplasma capsulatum</em> PCR test and urinary antigen were positive, so an antifungal treatment with voriconazole was started. Visual adverse effects forced to change the antifungal schedule in both the length of treatment and the antifungal drug. With this measure the patient progressed favorably. The test of urinary <em>Histoplasma capsulatum</em> antigen and PCR amplification were key to make a diagnosis and also for a follow-up.</p></div>","PeriodicalId":21291,"journal":{"name":"Revista Iberoamericana De Micologia","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Problemas clínicos en Micología Médica: problema número 56\",\"authors\":\"Fernando Messina ,&nbsp;Emmanuel Marin ,&nbsp;Alejandro Sansostera ,&nbsp;Mercedes Romero ,&nbsp;Roxana Depardo ,&nbsp;Ricardo Negroni ,&nbsp;Blanca Leonel ,&nbsp;Gabriela Santiso\",\"doi\":\"10.1016/j.riam.2022.12.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>We present the case of a twenty six year-old woman with rheumatoid arthritis, treated with certolizumab. She sought medical attention due to cough, fever and night sweats. X-ray exam showed a miliary pneumonia. She was treated for tuberculosis and 50<!--> <!-->days later she presented with aphasia. Magnetic nuclear resonance revealed brain lesions. <em>Histoplasma capsulatum</em> PCR test and urinary antigen were positive, so an antifungal treatment with voriconazole was started. Visual adverse effects forced to change the antifungal schedule in both the length of treatment and the antifungal drug. With this measure the patient progressed favorably. The test of urinary <em>Histoplasma capsulatum</em> antigen and PCR amplification were key to make a diagnosis and also for a follow-up.</p></div>\",\"PeriodicalId\":21291,\"journal\":{\"name\":\"Revista Iberoamericana De Micologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Iberoamericana De Micologia\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1130140623000013\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MYCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Iberoamericana De Micologia","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1130140623000013","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MYCOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

我们提出的情况下,26岁的妇女与类风湿性关节炎,certolizumab治疗。她因咳嗽、发烧和盗汗而求医。x光检查显示是军人肺炎。她接受了肺结核治疗,50天后出现失语。核磁共振显示脑损伤。荚膜组织浆体PCR检测及尿抗原阳性,给予伏立康唑抗真菌治疗。视觉不良反应迫使抗真菌方案在治疗时间和抗真菌药物两方面发生改变。采取这种措施后,病人进展顺利。尿荚膜组织浆抗原检测和PCR扩增是诊断和随访的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Problemas clínicos en Micología Médica: problema número 56

We present the case of a twenty six year-old woman with rheumatoid arthritis, treated with certolizumab. She sought medical attention due to cough, fever and night sweats. X-ray exam showed a miliary pneumonia. She was treated for tuberculosis and 50 days later she presented with aphasia. Magnetic nuclear resonance revealed brain lesions. Histoplasma capsulatum PCR test and urinary antigen were positive, so an antifungal treatment with voriconazole was started. Visual adverse effects forced to change the antifungal schedule in both the length of treatment and the antifungal drug. With this measure the patient progressed favorably. The test of urinary Histoplasma capsulatum antigen and PCR amplification were key to make a diagnosis and also for a follow-up.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.90
自引率
0.00%
发文量
17
审稿时长
81 days
期刊介绍: Revista Iberoamericana de Micología (Ibero-American Journal of Mycology) is the official journal of the Asociación Española de Micología, Asociación Venezolana de Micología and Asociación Argentina de Micología (The Spanish, Venezuelan, and Argentinian Mycology Associations). The Journal gives priority to publishing articles on studies associated with fungi and their pathogenic action on humans and animals, as well as any scientific studies on any aspect of mycology. The Journal also publishes, in Spanish and in English, original articles, reviews, mycology forums, editorials, special articles, notes, and letters to the editor, that have previously gone through a scientific peer review process.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信