一个年轻人意外服用过量维生素D3。

IF 2 4区 医学 Q3 NUTRITION & DIETETICS
Zahra Nekoukar, Aliasghar Manouchehri, Zakaria Zakariaei
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引用次数: 0

摘要

维生素D3 (VD3)是一种脂溶性维生素,可以在体内积累,当大量摄入时,会增加25(OH) D水平,从而导致毒性。由于维生素D在体内的重要作用,维持25(OH) D水平大于30 ng/mL对整体健康至关重要。VD3中毒最常见的原因是制造错误或自我给药。目前,没有明确的数据表明VD3的剂量和持续时间会导致毒性。可耐受而不引起不良反应的VD3的最大日剂量尚未确定。长期补充的最大推荐量是每天2,000单位。维生素D3毒性(VDT)可以出现在各种情况下,从无症状到胃肠道,在严重的情况下伴有神经精神和危及生命的症状。我们报告一例29岁的男性在服用过量VD3超过2周后出现VDT症状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Accidental vitamin D3 overdose in a young man.

Vitamin D3 (VD3) is a fat-soluble vitamin that can accumulate in the body and lead to toxicity by increasing 25(OH) D levels when consumed in large amounts. Maintaining 25(OH) D levels greater than 30 ng/mL is crucial for overall health due to the significant role of vitamin D in the body. The most common causes of VD3 intoxication are manufacturing errors or self-administration. Currently, there is no definitive data on the dose and duration of VD3 consumption that leads to toxicity. The maximum daily doses of VD3 that can be tolerated without causing adverse effects are not established. The maximum recommended amount for long-term supplementation is 2,000 units per day. Vitamin D3 toxicity (VDT) can present in various scenarios, ranging from asymptomatic to gastrointestinal, and in severe cases with neuropsychiatric and life-threatening symptoms. We report the case of a 29-year-old man who presented with symptoms of VDT following an accidental overdose of VD3 over 2 weeks.

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来源期刊
CiteScore
5.00
自引率
4.30%
发文量
53
审稿时长
>12 weeks
期刊介绍: Since 1930 this journal has provided an important international forum for scientific advances in the study of nutrition and vitamins. Widely read by academicians as well as scientists working in major governmental and corporate laboratories throughout the world, this publication presents work dealing with basic as well as applied topics in the field of micronutrients, macronutrients, and non-nutrients such as secondary plant compounds. The editorial and advisory boards include many of the leading persons currently working in this area. The journal is of particular interest to: - Nutritionists - Vitaminologists - Biochemists - Physicians - Engineers of human and animal nutrition - Food scientists
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