宫颈鳞状移行细胞癌合并卵巢转移及良性勃勒纳瘤1例报告

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Angel Yordanov, Milen Karaivanov, Ivan Ivanov, Stoyan Kostov, Venelina Todorova, Ilko Iliev, Eva Tzoneva, Diana Strateva
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引用次数: 0

摘要

引言:宫颈癌是妇女中第四大最常见的恶性肿瘤,也是妇女死亡的第四大原因。宫颈癌的主要组织学类型是鳞状细胞癌,占所有病例的75%;腺癌- 10 - 25%;以及所有其他罕见的变异包括腺鳞癌和神经内分泌癌。鳞状移行性宫颈癌是一种极为罕见且研究较少的鳞状细胞癌亚型。病例报告:我们报告一例64岁女性早期鳞状移行癌。左侧卵巢及左侧输卵管有转移,右侧卵巢有良性勃勒纳瘤。讨论:虽然认为该宫颈癌亚型与鳞状细胞癌具有相同的危险因素和预后,但它更容易转移和复发。在宫颈和附件等附近的结构中扩散并不罕见。这是不可能告诉哪是主要焦点从免疫档案的病变。实际上,在这些情况下,最好的做法是在明确子宫颈、子宫和附件组织的状况之前,排除泌尿道中原发肿瘤的存在。勃勒纳瘤的存在提出了肿瘤从细胞群分化和潜在的尿路上皮分化之间的联系的可能性。结论:宫颈鳞状移行性宫颈癌是一种罕见的肿瘤,临床行为研究较少。尽管文献资料缺乏,但应将其视为一种更具侵袭性的鳞状细胞癌,因此应更积极地治疗和随访。本病例是第一例累及子宫颈、子宫内膜和附件结构并伴有勃勒纳瘤的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Squamotransitional Cell Carcinoma of the Uterine Cervix with Ovarian Metastasis and Benign Brenner Tumor: A Case Report
Introduction: Cervical cancer is the fourth most common malignancy in women and the fourth leading cause of death among women. The main histological types of cervical cancer are squamous cell carcinoma—75% of all cases; adenocarcinoma—10–25%; and all other rare variants including adenosquamous carcinoma and neuroendocrine carcinoma. Squamotransitional cervical cancer is an extremely rare and poorly studied subtype of squamous cell carcinoma. Case report: We present a case of a 64-year-old female patient with early-stage squamotransitional carcinoma. A metastasis was observed in the left ovary and the left fallopian tube and a benign Brenner tumor in the right ovary. Discussion: Although it is believed that this cervical cancer subtype shares the same risk factors and prognosis as squamous cell carcinoma, it is more likely to metastasize and recur. It is not unusual for spread to exist within nearby structures like the cervix and adnexa. It is impossible to tell which is the predominant focus from the immunoprofile of the lesions. Practically speaking, the best course of action in these situations is to rule out the presence of a primary tumor in the urinary tract before clarifying the condition of the cervix, uterus, and adnexal tissues. The presence of a Brenner tumor raises the possibility of a connection between the tumor’s differentiation from a cell population and potential urothelial differentiation. Conclusion: Squamotransitional cervical cancer is a rare tumor with a poorly studied clinical behavior. Despite a shortage of information in the literature, it should be regarded as a more aggressive variety of squamous cell carcinoma and, as such, should be treated and followed up more aggressively. This case is the first described with involvement of the cervix, endometrium, and adnexal structures and a concomitant Brenner tumor.
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