[氨苄西林/舒巴坦联合用药治疗呼吸道感染的疗效]。

Giornale italiano di chemioterapia Pub Date : 1989-01-01

P Mangiarotti, G Manara, G Grassi, G Gialdroni Grassi

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引用次数: 0

摘要

舒巴坦(S)与氨苄西林(A)联合使用可延长氨苄西林(Amp)对β -内酰胺酶产生菌株的活性。因此，这种组合在包括LRTI在内的许多临床情况下都是有用的。我们进行了一项临床试验，比较S-Amp与单独使用Amp治疗LRTI的临床和细菌学疗效。临床疗效方面，S-Amp组满意率为83.3%，Amp组满意率为82.3%。S-Amp和Amp组的致病菌根除率分别为87.5%和70.5%。

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[Activity of an ampicillin/sulbactam combination in respiratory infections].

The combination of sulbactam (S) plus ampicillin (A) extends the activity of ampicillin (Amp) against beta-lactamase producing strains. This combination is therefore useful in many clinical situations including LRTI. A clinical trial was carried out to evaluate the clinical and bacteriological efficacy of S-Amp in LRTI in comparison with Amp alone. Concerning clinical outcome the results were satisfactory in 83.3% of cases for S-Amp group and 82.3% of cases for Amp group. Pathogen eradication was achieved in 87.5% and 70.5% of cases respectively for the S-Amp and Amp group.

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Giornale italiano di chemioterapia

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