心血管疾病系统(生物-心理-社会)预测模型的建立。第二部分

O. Yu. Shchelkova, M. V. Iakovleva, D. A. Eremina, R. Yu. Shindrikov, N. E. Kruglova, I. A. Gorbunov, E. A. Demchenko
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引用次数: 0

摘要

作者试图设计和验证心血管疾病的综合(医学、社会和心理)预后模型,该模型将涵盖患者的疾病、治疗和生活功能的各个方面。一套多学科的方法被用来实现这一目标。该研究包括437名患有冠心病或慢性心力衰竭的患者,包括缺血性和非缺血性病因,他们被转介进行心血管手术,并接受了手术干预。文章的第二部分给出了最后三个阶段的研究结果。这些指标如下:5)所研究的指标分为以下亚组:“当前状态因素”(反映患者当前的心理状态,表征其认知和情绪-情感领域)和“基线因素”(反映疾病的相对稳定特征、患者的社会行为和个人特征)。6)重新进行因子分析,得到11个次要因子:“当前状态因素”组(“心理健康”、“面对心脏病的生活质量”、“焦虑导致的非语言认知功能下降”、“积极情绪和认知状态”、“遗忘功能状态”)中有5人,“基线因素”组(“面对疾病的非建设性行为”、“职业动机和心血管疾病的严重程度”、“冠心病的社会心理风险因素”、“患者动机”、紧张和慢性心力衰竭的严重程度”,“社会支持和弹性”,“依从性行为和理性思维”)。7)我们使用数学建模和神经网络来确定上述因素的预测价值,并构建了一个系统的预测模型,该模型能够在任何给定时间(手术后几天)预测所有“当前状态因素”的值,准确率高达80%。在未来,我们计划为“基线因素”设计一个模型。在心脏手术准备阶段识别与预后相关的患者特征可以帮助优化患者在此期间的心理帮助,并个性化术后康复计划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
On the development of a systemic (biopsychosocial) prediction model for cardiovascular disease. Part II
The authors have attempted to design and verify a model of comprehensive (medical, social and psychological) prognosis in cardiovascular disease, which would cover aspects of patients’ illness, treatment and life functioning. A multidisciplinary set of methods was used to realise the aim. The study included 437 patients suffering from coronary heart disease or chronic heart failure, both of ischaemic and non-ischaemic etiology, who were referred for cardiovascular surgery, and who had undergone surgical intervention. Part II of the article presents the results of the 3 final stages of the study. These are the following: 5) The studied indicators were divided into the following subgroups: “Current state factors” (reflecting the patients’ current psychological state, characterising their cognitive and emotional-affective spheres) and “Baseline factors” (reflecting relatively stable characteristics of the disease, socio-behavioural and personal features of the patients). 6) A new factor analysis was performed, resulting in 11 secondary factors: 5 in the group of “Current state factors” (“Psychological well-being”, “Quality of life in the face of cardiac disease”, “Reduced non-verbal cognitive functions due to anxiety”, “Positive mood and cognitive state”, “State of mnestic function”) and 6 in the group of “Baseline factors” (“Non-constructive behaviour in the face of disease”, “Occupational motives and severity of cardiovascular disease”, “Psychosocial risk factors for coronary heart disease”, “Patient motivation, tension and severity of chronic heart failure”, “Social support and resilience”, “Adherent behaviour and rational thinking”). 7) We used mathematical modelling and a neural network to determine the prognostic value of the above factors and to construct a systematic prediction model that will be capable of predicting the value of all “Current state factors” at any given time (days after surgery) with an accuracy of up to 80%. In the future, we plan to design a model for the “Baseline factors”. The identification of prognostically relevant patients’ characteristics at the stage of preparation for cardiac surgery can help to optimise psychological help for the patient during this time and individualise the postoperative rehabilitation programme.
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