自闭症的病因

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Gary Steinman
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引用次数: 0

摘要

目前,自闭症的致病因素似乎是许多新生儿和婴儿体内胰岛素样生长因子-1 (IGF1)和维生素D3供应不足,从而导致脑神经发育中髓磷脂持续不足。各种畸形的神经网络会持续到成年。特别值得关注的是妊娠暴露于发热病毒条件下,白细胞介素抑制IGF1的产生。在许多这种情况下,新生儿的母乳喂养可能是预防性的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Etiology of Autism
The causative factor for autism now appears to be a deficient supply of insulin-like growth factor-1 (IGF1 ) and vitamin D3 in many newborn and infants, thereby leading to persistently insufficient myelin in developing cranial nerves. Various malformed neurologic networks last into adulthood. Of particular concern is a pregnancy exposed to febrile viral conditions, where interleukins suppress IGF1 production. Breastfeeding of the newborn may be preventative in many such cases.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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