自闭症的病因

IF 1.9 4区医学 Q4 NEUROSCIENCES

Restorative neurology and neuroscience Pub Date : 2023-09-30 DOI:10.33425/2692-7918.1049

Gary Steinman

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引用次数: 0

摘要

目前，自闭症的致病因素似乎是许多新生儿和婴儿体内胰岛素样生长因子-1 (IGF1)和维生素D3供应不足，从而导致脑神经发育中髓磷脂持续不足。各种畸形的神经网络会持续到成年。特别值得关注的是妊娠暴露于发热病毒条件下，白细胞介素抑制IGF1的产生。在许多这种情况下，新生儿的母乳喂养可能是预防性的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Etiology of Autism

The causative factor for autism now appears to be a deficient supply of insulin-like growth factor-1 (IGF1 ) and vitamin D3 in many newborn and infants, thereby leading to persistently insufficient myelin in developing cranial nerves. Various malformed neurologic networks last into adulthood. Of particular concern is a pregnancy exposed to febrile viral conditions, where interleukins suppress IGF1 production. Breastfeeding of the newborn may be preventative in many such cases.

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来源期刊

Restorative neurology and neuroscience 医学-神经科学

CiteScore

5.40

自引率

3.60%

发文量

审稿时长

>12 weeks

期刊介绍： This interdisciplinary journal publishes papers relating to the plasticity and response of the nervous system to accidental or experimental injuries and their interventions, transplantation, neurodegenerative disorders and experimental strategies to improve regeneration or functional recovery and rehabilitation. Experimental and clinical research papers adopting fresh conceptual approaches are encouraged. The overriding criteria for publication are novelty, significant experimental or clinical relevance and interest to a multidisciplinary audience. Experiments on un-anesthetized animals should conform with the standards for the use of laboratory animals as established by the Institute of Laboratory Animal Resources, US National Academy of Sciences. Experiments in which paralytic agents are used must be justified. Patient identity should be concealed. All manuscripts are sent out for blind peer review to editorial board members or outside reviewers. Restorative Neurology and Neuroscience is a member of Neuroscience Peer Review Consortium.