印度妊娠期贫血的预防和管理:挑战和机遇

Prema Ramachandran, K. Kalaivani
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摘要

70年前,超过80%的印度孕妇患有贫血症。大约四分之三的贫血是由于营养缺乏:铁(最常见),叶酸(第二)和维生素B12(不常见)。妊娠期贫血与较高的产妇发病率和死亡率、低出生体重和高围产期死亡率有关。贫血的检测和适当管理,包括肠外铁治疗和重症监护,是印度产前保健的重要组成部分,但只有约10%的妇女能够获得产前保健。20世纪70年代,国家妊娠贫血方案的重点是确定所有孕妇并向她们提供铁和叶酸补充剂。补充的覆盖率和依从性较低。1990年,初级保健基础设施建立后,贫血控制方案开始对贫血妇女进行检测和提供适当治疗。三级保健中心实施了这一“检测和治疗”战略。在初级和二级保健机构中,没有准确的贫血诊断检测。由于在所有级别的护理中缺乏准确的Hb估计,因此不可能根据Hb水平提供适当的治疗。因此,所有孕妇在怀孕期间继续服用一片IFA。在接下来的20年里,产前保健和IFA补充的覆盖率有所提高,但补充的依从性很低,因为大约三分之一的孕妇服用IFA有胃肠道副作用。尽管存在这些问题,但在2002年至2015年期间,严重和中度贫血的患病率有所下降。为了加速妊娠期贫血的下降,该国正在将重点放在孕妇的“检测和治疗”战略上,使用准确的血红蛋白估计方法并提供适当的治疗。营养教育旨在改善怀孕前和怀孕期间的铁摄入量,重点是饮食多样化和使用铁强化盐或谷物。将通过国家调查监测进展情况,并将针对具体地点对方案作出适当的中期修改。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevention and management of Anaemia in Pregnancy in India: Challenges and Opportunities
Seven decades ago, over 80% of Indian pregnant women were anaemic. About 3/4th of anaemia was due to nutritional deficiencies of: iron (most common), folic acid (second) and vitamin B12 (not as common). Anaemia in pregnancy was associated with higher maternal morbidity and mortality, low birth weight and high perinatal mortality. Detection and appropriate management of anaemia, including parenteral iron therapy and intensive care for severe anaemia were important components of antenatal care in India, but only about 10% of women had access to antenatal care. In 1970s the national programme for anaemia in pregnancy focussed on identifying all pregnant women and providing them iron and folic acid (IFA) supplementation. The coverage and compliance with supplementation were low. In 1990 when the primary health care infrastructure was established, the anaemia control programme embarked on testing and providing appropriate treatment to anaemic women. The tertiary care centres operationalised this “test and treat” strategy. In primary and secondary care settings, accurate test for diagnosis of anaemia was not available. In the absence of accurate Hb estimation at all levels of care, it was not possible to provide appropriate treatment based on Hb levels. So, all pregnant women continued to receive one tablet of IFA throughout pregnancy. Over the next two decades, coverage under antenatal care and IFA supplementation improved but compliance with supplementation was low because about a third of pregnant women had gastrointestinal side effects with IFA. Despite these problems, between 2002 and 2015, there had been a decline in the prevalence of severe and moderate anaemia. To accelerate the decline in anaemia in pregnancy the country is focusing on the ‘test and treat’ strategy in pregnant women using an accurate method for Hb estimation and providing appropriate treatment. Nutrition education to improve iron intake prior to and during pregnancy, is focussing on dietary diversification and use of iron fortified salt or cereals. Progress will be monitored through national surveys and locale specific appropriate mid-course modifications in the programme will be made.
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