伊拉克埃尔比勒Raparin教学医院毛细支气管炎及其不同管理方法

Sasan Loqa Hanna
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摘要

背景:尽管细支气管炎的患病率、全球影响、经济负担、死亡率和发病率都与细支气管炎有关,但临床管理似乎仍然很困难。目的:介绍毛细支气管炎的多种治疗方案,总结最安全、最有效的治疗方法,以帮助拉帕林教学医院制定循证治疗方案。患者和方法:本研究设计为随机对照试验,共纳入125例毛细支气管炎患儿,分为A、B、C、D、E 5组,每组25例。除A组患者仅给予支持治疗外,其余各组患者均给予氧、静脉输液等支持治疗。研究于2022年1月1日至8月1日在伊拉克埃尔比勒市Raparin教学医院的住院病房进行。婴幼儿年龄1 ~ 60月龄,临床诊断为毛细支气管炎。结果:不同治疗方式(组)与治疗后咳嗽相关(p:0.006),不同治疗方式(组)与治疗后副肌使用相关(p:0.037),差异无统计学意义(p:0.538)。结论:B组(吸入性支气管扩张剂)和D组(吸入性支气管扩张剂加静脉类固醇)患者在咳嗽、副肌使用、呼吸频率(呼吸急促)、发热和鼻炎消退时间、静脉输液时间、氧疗时间和住院时间等方面均有较好的缓解率。关键词:毛细支气管炎,喘息,治疗,随机临床试验,伊拉克
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bronchiolitis and its Different Ways of Management in Raparin Teaching Hospital, Erbil-Iraq
Background: Despite the prevalence, global impact, financial burden, and mortality and morbidity related to bronchiolitis, clinical management still seems to be difficult. Objective: To describe the diversity medical treatment options used to manage bronchiolitis and conclude the safest and most effective way to treat it in order to help the development of an evidence based treatment protocol at Raparin teaching hospital. Patients and Methods: This current study design was randomized controlled trial, in which total of 125 children presented with bronchiolitis enrolled in our study, we divided them into five groups (A, B, C, D and E), each of 25 cases. All the groups received supportive treatment in the form of oxygen and intravenous (IV) fluid in addition to specific treatment except group A subjects who received supportive treatment only. The treatments were The study was conducted at the inpatient wards of Raparin teaching hospital in Erbil city-Iraq, from the period of 1st January to 1st August 2022. The infants and children’s age was ranging from 1 to 60 months with clinical diagnosis of bronchiolitis. Results: There was non-significant statistical association between treatment groups and presence of wheeze after treatment (p:0.538), while statistically significant association between various treatment modalities (groups) and cough after treatment (p:0.006) in the same way the association was significant with accessory muscle use after treatment (p:0.037). Conclusion: Generally patients in groups B (inhaled bronchodilator) and D (inhaled bronchodilator and intravenous steroids) had better response rates in terms of cough, accessory muscle use, respiratory rate (tachypnea), time to resolution of fever and coryza, duration of IV fluid therapy, oxygen therapy and hospital stay. Which conclude using of inhaled bronchodilator and IV steroid Keywords: Bronchiolitis, Wheeze, Treatment, Randomized clinical trial, Iraq
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