利用深度学习从DNA序列预测糖尿病

Lena abed ALraheim Hamza, Hussein Attya Lafta, Sura Zaki Al-Rashid
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引用次数: 0

摘要

糖尿病是一种以血糖水平升高为特征的慢性代谢紊乱。它有不同的表现形式,以1型和2型最为普遍。1型糖尿病是由自身免疫破坏胰岛素生成细胞引起的,而2型糖尿病主要是由胰岛素抵抗引起的。尽管治疗取得了进步,但准确检测和预测糖尿病仍然具有挑战性。早期诊断对于有效管理和预防并发症至关重要。另一个障碍是解释包括DNA测序在内的大量健康数据,这给保健专业人员确定相关模式和关联带来了困难。人工智能(AI)通过开发和训练深度学习算法来分析健康数据和DNA序列,在医疗保健领域带来了希望。本研究重点应用卷积神经网络(cnn)算法和长短期记忆(LSTM)算法,基于DNA测序预测糖尿病类型。该研究旨在利用CNN和LSTM的能力,以分析图像和序列数据而闻名,以准确分类糖尿病类型。本文提出的CNN-LSTM模型的实验结果显示了卓越的性能,在包含DNA测序和相应糖尿病类型的标记数据集上实现了100%的记录准确率。该模型的评估包括几个指标,包括准确性、召回率、精度和F1分数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictive Diabetes Mellitus From DNA Sequences Using Deep Learning
Diabetes is a chronic metabolic disorder characterized by elevated blood sugar levels. It manifests in different forms, with type 1 and type 2 being the most prevalent. Type 1 diabetes results from the autoimmune destruction of insulin-producing cells, whereas type 2 diabetes primarily stems from insulin resistance. Despite advancements in treatment, accurate detection and prediction of diabetes remain challenging. Early diagnosis is crucial for effective management and prevention of complications. Another obstacle lies in interpreting vast amounts of health data, including DNA sequencing, which poses difficulties for healthcare professionals in identifying relevant patterns and associations. Artificial intelligence (AI) holds promise in healthcare by developing and training deep learning algorithms to analyze health data and DNA sequences. The research paper focuses on applying both Convolutional Neural Networks (CNNs) algorithm, in addition to Long Short-Term Memory (LSTM) algorithm for predicting types of diabetes based on DNA sequencing. The study aims to leverage the power of CNN and LSTM, known for their proficiency in analyzing image and sequence data, to accurately classify diabetes types. The experimental results of the proposed CNN-LSTM model showcased remarkable performance, achieving a recorded accuracy of 100% on a labeled dataset that included DNA sequencing and corresponding diabetes types. The model's evaluation encompassed several metrics, including accuracy, recall, precision, and the F1 score.
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