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引用次数: 0
摘要
背景对环氧树脂过敏大多是职业性的，尤其是建筑行业的从业人员。非职业环氧树脂过敏的病例则较少见。方法分析皮肤科信息网络（IVDK）中的相应数据；文献综述。结果在 2013-2022 年的 IVDK 中，职业性皮炎（OD）患者对环氧树脂的阳性反应率为 2.4-4.0%，无 OD 患者为 0.8-1.5%。对活性稀释剂和固化剂的伴随反应证明，无 OD 的患者也接触过环氧树脂。对环氧树脂过敏的患者对其他基线系列过敏原产生反应的风险也会增加。非职业环氧树脂过敏的病例报告涉及浇铸树脂的工作。讨论非职业性环氧树脂过敏不仅可能来自狭义的 DIY 活动，在询问病史时也应考虑到这一点。环氧树脂和香料过敏之间的联系并没有超出接触性过敏之间的一般联系。
Sensitization to epoxy resin is mostly acquired occupationally, with those employed in the construction industry being particularly affected. Cases of non-occupational epoxy resin allergy are observed less frequently. In the literature, an association between epoxy resin allergy and fragrance allergy is postulated.
Methods
Analysis of corresponding data from the Information Network of Departments of Dermatology (IVDK); literature review.
Results
In the IVDK 2013–2022, the rate of positive reactions to epoxy resin in patients with occupational dermatitis (OD) was 2.4–4.0%, in patients without OD 0.8–1.5%. Accompanying reactions to reactive diluents and hardeners prove an exposure to epoxy resins also in patients without OD. Patients sensitized to epoxy resin have an increased risk of reactions to other baseline series allergens. Case reports of non-occupational epoxy resin allergy concern work with casting resins. However, epoxy resin exposure is also possible, for example, from three-dimensional (3D) printing finishes or products for hoof repair in horses.
Discussion
Non-occupational epoxy resin allergy may be acquired not only from do-it-yourself activities in the narrow sense, which should be considered when taking the medical history. The association between epoxy resin and fragrance allergy does not go beyond the general level of associations between contact allergies with each other.
期刊介绍：
Allergo Journal International is the official Journal of the German Society for Applied Allergology (AeDA) and the Austrian Society for Allergology and Immunology (ÖGAI). The journal is a forum for the communication and exchange of ideas concerning the various aspects of allergy (including related fields such as clinical immunology and environmental medicine) and promotes German allergy research in an international context. The aim of Allergo Journal International is to provide state of the art information for all medical and scientific disciplines that deal with allergic, immunological and environmental diseases. Allergo Journal International publishes original articles, reviews, short communications, case reports, and letters to the editor. The articles cover topics such as allergic, immunological and environmental diseases, the latest developments in diagnosis and therapy as well as current research work concerning antigens and allergens and aspects related to occupational and environmental medicine. In addition, it publishes clinical guidelines and position papers approved by expert panels of the German, Austrian and Swiss Allergy Societies.
All submissions are reviewed in single-blind fashion by at least two reviewers.
Originally, the journal started as a German journal called Allergo Journal back in 1992. Throughout the years, English articles amounted to a considerable portion in Allergo Journal. This was one of the reasons to extract the scientific content and publish it in a separate journal. Hence, Allergo Journal International was born and now is the international continuation of the original German journal. Nowadays, all original content is published in Allergo Journal International first. Later, selected manuscripts will be translated and published in German and included in Allergo Journal.
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